Latest technologies from Wayne State Universityhttp://wayne.technologypublisher.comBe the first to know about the latest inventions and technologies available from Wayne State Universityen-USSun, 19 Feb 2017 19:54:45 GMTWed, 15 Feb 2017 08:05:57 GMThttp://blogs.law.harvard.edu/tech/rssttoinfo@wayne.eduCopyright 2017, Wayne State UniversityToxicological high throughput screens based on prioritized differentiation of mouse viable potency reporter, and viable first differentiated lineage reporter, mouse embryonic stem cellshttp://wayne.technologypublisher.com/technology/24072Wed, 15 Feb 2017 08:05:57 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/24072Topical treatment with TGFbeta3 to facilitate skin and corneal wound healing in diabetic patientshttp://wayne.technologypublisher.com/technology/24024Fri, 10 Feb 2017 13:42:47 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/24024CJ4.1A and CJ4.3C Rat Conjunctival Epithelial Cell Lineshttp://wayne.technologypublisher.com/technology/23894Mon, 30 Jan 2017 10:40:25 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/23894New Method of Treating B-Cell Cancershttp://wayne.technologypublisher.com/technology/23834Thu, 19 Jan 2017 09:16:24 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/23834Smart Artificial Muscles (SAM): Lightweight, soft self-powered actuators to assist mobilityhttp://wayne.technologypublisher.com/technology/22086Wed, 25 May 2016 11:03:29 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/22086Addressing Co-Channel Interference with PRK-Based Scheduling for Predictable Link Reliability in Wireless Networked Sensing and Controlhttp://wayne.technologypublisher.com/technology/22084Reliable wireless communication is a basic enabler for networked sensing and control in many cyber-physical systems, yet co-channel interference is a major source of uncertainty in wireless communication. Integrating the protocol model's locality and the physical model's high fidelity, the physical ratio-K (PRK) interference model bridges the gap between the suitability for distributed implementation and the enabled scheduling performance in existing interference models, and it is expected to serve as a foundation for distributed, predictable interference control. To realize the potential of t...Wed, 25 May 2016 09:21:37 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/22084Topical IL-1Ra (anakinra) in the form of gel to treat persistent diabetic skin and corneal woundshttp://wayne.technologypublisher.com/technology/22083Wed, 25 May 2016 09:14:21 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/22083Antibacterial activity of natural compounds and their synthetic analogue: A potential new antibiotic with potent activity against multiple drug resistant bacterial pathogenshttp://wayne.technologypublisher.com/technology/19365Tue, 12 May 2015 06:48:47 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/19365Smart Anesthesia Monitorhttp://wayne.technologypublisher.com/technology/15821Technology Summary:  WSU researchers have developed a technology to assist anesthesiologists using real-time monitoring, outcome prediction and anesthesia decision support in operating rooms. This smart anesthesia monitoring system allows the physician to look into the near-future and make decisions that are more objective, timely, and accurate. The core of the technology is a novel information processing methodology that uses measured drug rates, physiological signals and real-time data analysis to establish and update individual patient models. Background: General anesthesia is an integral p...Fri, 05 Sep 2014 09:18:02 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/15821IMAGING TUMORS USING PHOSPHOAMIDATE DERIVATIVES OF FAUhttp://wayne.technologypublisher.com/technology/15775Fri, 22 Aug 2014 12:42:17 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/15775Whole body model of a 10-year-old child for pediatric injury predictionhttp://wayne.technologypublisher.com/technology/13504Fri, 11 Oct 2013 08:07:14 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/13504Modified Ectodomain of Human EGFR as a Potential Anticancer Agenthttp://wayne.technologypublisher.com/technology/13292Thu, 15 Aug 2013 12:32:17 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/13292Translation Regulated (TR)-Mediated Gene Expression: Novel Expression and Reporter Vectorshttp://wayne.technologypublisher.com/technology/13289Wed, 14 Aug 2013 10:49:58 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/13289Improved DW-MRI analysis methods for detecting motor functionshttp://wayne.technologypublisher.com/technology/13288Wed, 14 Aug 2013 09:06:16 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/13288Co-polymer Stabilizers for Pressured Metered Dose Inhalers (pMDIs)http://wayne.technologypublisher.com/technology/13287Wed, 14 Aug 2013 09:04:14 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/13287Electrowetting on Dielectric (EWOD) Using Graphenehttp://wayne.technologypublisher.com/technology/12732Mon, 10 Jun 2013 10:08:30 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/12732Porous Biodegradable Polymers for Bone Graftshttp://wayne.technologypublisher.com/technology/12731Technology Summary: A novel polymer nanocomposites has been developed as a potential alternative to autografts and allografts in orthopedic procedures requiring bone grafting. Supercritical CO2 processing of resorbable polymer/nano-clay mixtures results in the formation of porous nanocomposite constructs which exhibit biocompatibility and significant improvements in mechanical properties (2.5-fold increase in compressive strength compared with pure polymer constructs). Improvements in the mechanical properties of the constructs are related to the dispersion of nano-clay within the polymer matr...Mon, 10 Jun 2013 10:07:49 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/1273167DHB Grapefruit Inhibitorhttp://wayne.technologypublisher.com/technology/12730Mon, 10 Jun 2013 10:04:48 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/12730Ruthenium-based caging of nitrile-containing enzyme inhibitorshttp://wayne.technologypublisher.com/technology/12395Mon, 29 Apr 2013 10:33:19 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/12395Laser Spray Ionization (LSI) Method for Mass Spectrometry Imaginghttp://wayne.technologypublisher.com/technology/12392Technology Summary: Laser Spray Ionization (LSI) is a novel inlet ionization method for mass spectrometry invented at WSU which can be used to create predominately multiply charged ions from solid samples at atmospheric pressure. Unlike MALDI ionization methods which are typically limited to producing singly charged species for larger molecules, LSI produces ions similar to Electrospray Ionization (ESI) methods without the need for a solvent or voltage. With higher charged ions, LSI extends the mass range (m/z) for high MW analytes which is typically limited in high resolution mass spec instru...Fri, 26 Apr 2013 12:21:02 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/12392Nanoparticle Method to Stabilize Suspension-Based pMDI HFA Formulationshttp://wayne.technologypublisher.com/technology/12376Tue, 23 Apr 2013 12:55:51 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/12376Controllable Laser Fabrication of Conical Nano-Tips on Semiconductor Thin Filmshttp://wayne.technologypublisher.com/technology/12375Field emitter displays (FED) represents the next phase in display technology. A team of researchers at Wayne State University has invented a new process that creates consistently sized and uniformly spaced nano-sized conical tips on semiconductor thin films that may have application in a number of areas including field emitter arrays for flat-panel displays. The tips are up to 1 mm in height with radii on the order of several tens of nanometers. Creating conical tips on semiconductor thin films could provide the reduction in cost necessary to bring flat panel displays in line with CRTs in term...Tue, 23 Apr 2013 11:50:42 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/12375Dual action nanocarrier combining CXCR4 antagonist and polyplex gene delivery for treatment of metastatic cancer and other diseaseshttp://wayne.technologypublisher.com/technology/10774Mon, 10 Sep 2012 10:41:45 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/10774Drug-Dendrimer Nanoparticles for Targeted Treatment of Neuroinflammationhttp://wayne.technologypublisher.com/technology/9901 Highly effective dendrimer-drug based compositions and methods for treatment have been developed that target neuroinflammation both in the brain and the retina upon intravenous administration. The nanodevices overcome the blood-brain barrier (BBB) and deliver drugs to target cells (activated microglia and astrocytes) producing dramatic therapeutic improvements. Benefits: Many promising pharmaceutical compounds fail to reach target tissue or fail to remain in the target area long enough to work. The drug-dendrimer nanoparticles invented at WSU allow the drug to be carried to target a...Thu, 02 Aug 2012 13:46:34 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/9901Next Generation MRI Contrast Imaging Agenthttp://wayne.technologypublisher.com/technology/9900Thu, 02 Aug 2012 12:40:28 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/9900<![CDATA[Intelligent Autonomous Camera Control for Robotics with Medical, Military, & Space Applications]]>http://wayne.technologypublisher.com/technology/9857Currently, during robotic surgery the surgeon must interrupt the operation and shift controls to move the camera arm of the robot, causing a distraction for the surgeon.  Researchers from Wayne State University’s Electrical and Computer Engineering Department and the School of Medicine have jointly developed a new method for camera movement based on internally tracking (via kinematics of the robot) the locations of the end-effectors and automatically moving the camera arm to follow and zoom into the region where the surgeon is working.  The system can be configured to ensure that the tracked e...Tue, 24 Jul 2012 13:10:59 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/9857Integration of 1-D MnO2 Nanowire and 2-D Graphene to 3-D Composites and their Applications in High-Energy, High-Power and Low-Cost Aqueous Supercapacitorshttp://wayne.technologypublisher.com/technology/9811Wed, 18 Jul 2012 13:58:07 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/9811In-Cylinder Cycle-by-Cycle NOx Measuring Technique in Spark Ignited Engineshttp://wayne.technologypublisher.com/technology/9212Tue, 24 Apr 2012 07:07:53 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/9212Broadcast Messaging Systemhttp://wayne.technologypublisher.com/technology/8523Mon, 19 Dec 2011 10:52:01 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/8523Enhanced Peripheral Detection Test-I (EPDT-I) Enhanced Peripheral Detection Test-II (EPDT-II)http://wayne.technologypublisher.com/technology/8513Thu, 15 Dec 2011 11:49:04 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/8513Atomic Layer Deposition of Transition Metal Thin Filmshttp://wayne.technologypublisher.com/technology/8235 Wayne State University researchers have circumvented precursor reactivity problems by developing a three-step deposition scheme that entails a transition metal precursor, an organic acid, and a reducing agent. This novel process can produce high purity, low resistivity copper films at 100 °C, which is a significant breakthrough in transition metal ALD processes. Microelectronics device dimensions are scheduled to reach 22 nm by 2012, and existing deposition processes will soon not be able to provide the required level of thickness control and conformality, especially in high aspect ratio feat...Wed, 23 Nov 2011 07:43:34 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/8235Marangoni Optofluidic Tweezers (MOT)http://wayne.technologypublisher.com/technology/8234Wed, 23 Nov 2011 07:43:33 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/8234A Flexible Biocompatible Graphene Sensor for Point-of-care Diagnosishttp://wayne.technologypublisher.com/technology/8233Wed, 23 Nov 2011 07:43:32 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/8233Solid Zn-base Catalysts for Simultaneous Transesterification and Esterificationhttp://wayne.technologypublisher.com/technology/8232Wed, 23 Nov 2011 07:43:32 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/8232Graphene based support matrix to anchor bifunctional catalyst for Lithium-Air batterieshttp://wayne.technologypublisher.com/technology/8223Tue, 22 Nov 2011 10:30:12 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/8223Dispersion-optimized Silicon nanoparticle (SiNP)/Graphene composite anode for high performance Lithium ion battery (LIB)http://wayne.technologypublisher.com/technology/8141Mon, 07 Nov 2011 10:04:39 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/8141Nano-beaker array formation process and its use for high-throughput loading and crystallization screening and other lab-on-the-chip applicationshttp://wayne.technologypublisher.com/technology/8140Mon, 07 Nov 2011 10:04:38 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/8140Compositions, Process, and Method for Producing Hybrid Green Cements and Their Concrete Productshttp://wayne.technologypublisher.com/technology/8139Mon, 07 Nov 2011 10:04:37 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/8139Simultaneous Ion Sensing and Gas sampling in Combustion Engine Cylinders and Other Combustion Systemshttp://wayne.technologypublisher.com/technology/7638Tue, 19 Jul 2011 08:13:21 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/7638In-Cylinder Cycle-by-Cycle Soot Measuring Technique in Diesel Engineshttp://wayne.technologypublisher.com/technology/7637Currently there is no device or technology to allow for onboard soot measurement in diesel engine vehicles. Wayne State University researchers have developed a technique which utilizes the ion current signal produced from an ion current sensor installed in the combustion chamber of each cylinder to determine the quantity of soot present in the cylinder at the end of the combustion process.  During each cycle, the cylinder’s exhaust valve opens and its contribution in the total soot emitted in the exhaust of multi-cylinder diesel engines is measured.Additionally, the input signal from each cyli...Tue, 19 Jul 2011 08:13:20 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/7637Autonomous Operation of Electronically Controlled Diesel Engines on a Multitude of Fuels Using Ion Current and Other Combustion Sensorshttp://wayne.technologypublisher.com/technology/7633Mon, 18 Jul 2011 10:53:12 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/7633GlyB4 Fusion with Neuregulin Heparin-Targeting Domain to Block Neuregulin Signalinghttp://wayne.technologypublisher.com/technology/7114Mon, 16 May 2011 14:00:13 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/7114Peptide Antimicrobialhttp://wayne.technologypublisher.com/technology/7057Tue, 03 May 2011 06:51:46 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/7057First Row Transition Metal Diazadiene Film Growth Precursorshttp://wayne.technologypublisher.com/technology/7052Mon, 02 May 2011 10:48:18 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/7052Vibro-acoustic metamaterial with mass and flexible stem arrayhttp://wayne.technologypublisher.com/technology/7051Mon, 02 May 2011 10:42:22 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/7051Development of a High Strength High Toughness (HSHT) Bainitic Steelhttp://wayne.technologypublisher.com/technology/7049This invention is a unique composition of steel when subjected to a non-conventional austempering process results in the following physical property advantages over high strength low alloy (HSLA) steel:- Twice the strength- Almost three times the fracture toughnessAustempering is a process typically used to produce specialty cast iron products but is not employed in the processing of steel. The austempering process that is unique to this invention alters both the temperature and time profiles of iron austempering to increase nucleation sites resulting in a finer grain microstructure th...Fri, 29 Apr 2011 10:56:29 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/7049Concussion Reduction Helmethttp://wayne.technologypublisher.com/technology/6576Thu, 10 Mar 2011 07:16:45 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/6576Vibration Energy Harvesting Device Based on Air-Spaced Piezoelectric Cantilevershttp://wayne.technologypublisher.com/technology/5753Tue, 05 Oct 2010 12:25:02 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5753Guidance and Control System for Under Actuated Marine Surface Vesselshttp://wayne.technologypublisher.com/technology/5641Tue, 21 Sep 2010 06:58:36 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5641Combined Homogeneous and Heterogeneous Catalytic Transesterification Process for Biodiesel Productionhttp://wayne.technologypublisher.com/technology/5555WSU researchers developed a combined heterogeneous and homogeneous catalyst that reduces overall production costs, expands feedstock options, and enables large volume production in a continuous process as compared to traditional homogeneous biodiesel catalysts. This unique catalytic transesterification process works better with ethanol compared to methanol can be used in continuous or batch biodiesel production processes and has advantages over existing homogeneous catalyst processes including:- Eliminates use of caustic catalysts that generate significant soap formation and environmental iss...Tue, 17 Aug 2010 12:31:18 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5555Regulators of Peritoneal Healing and Adhesion Developmenthttp://wayne.technologypublisher.com/technology/5482Thu, 15 Jul 2010 11:20:03 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5482Repurposing AKT Inhibitors for the Treatment of Protein Misfolding and Protein Trafficking Diseaseshttp://wayne.technologypublisher.com/technology/5339Tue, 22 Jun 2010 06:18:53 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5339High Efficient Reagent that Transfers Protein into the Living Mammalian Cellshttp://wayne.technologypublisher.com/technology/5338 This invention is a new protein transduction method for efficient delivery of exogenous proteins into mammalian cells. In contrast to known protein transduction methods, this new approach has the capability of targeting transduced proteins to different cellular compartments, as well as protecting the proteins from degradation by cellular proteases. The reagent for delivery of the proteins is composed of cationic agents, lipids and enhancer in a carrier. The Approach uses bacteria to produce recombinant proteins that are then modified with the reagent and delivered into mammalian cells...Tue, 22 Jun 2010 06:18:47 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5338Inhibitors of Matrix Metalloproteinaseshttp://wayne.technologypublisher.com/technology/5337 Wayne State University researchers and academic collaborators have prepared the first reported mechanism-based inhibitors for matrix metalloproteinases (MMPs). One of the novel compounds (SB-3CT) shows selectivity for the gelatinases (two members of the MMP family), which have been implicated in various pathological conditions including, but not limited, to the process of tumor metastasis and angiogenesis, cardiovascular diseases and neurological conditions. In vivo results from WSU and academic collaborators have shown promise in cancer therapy (in T-cell lymphoma and prostate cancer...Tue, 22 Jun 2010 06:18:32 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5337Fuel Injector to Work as an Ionization Sensor and as an Injection Signal Detector in Electronically Controlled Fuel Injection Systems in Diesel and Direct Injection Gasoline Engineshttp://wayne.technologypublisher.com/technology/5285Fri, 04 Jun 2010 07:01:31 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5285Peptides Representing Genus-Specific Chlamydial Antigens for Vaccine Peptide Vaccines for Chlamydia to be Delivered Orally or by Other Mucosal Routeshttp://wayne.technologypublisher.com/technology/5228Tue, 18 May 2010 06:29:39 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5228Using Flagellin to Prevent and to Treat Inflammation Associated Gram Negative Bacterial Infectionhttp://wayne.technologypublisher.com/technology/5225Detailed Description The existence of multipotent stem cells within the adult brain has been debated for some time. While the identity of this cell has been unknown it is clear that stem cells reside in specialized tissue (subventricular zone and subgranular zone) and that local microenvironments regulate their differentiation and self-renewal. WSU researchers have identified capillary pericytes as possessing pluripotent stem cell capability. One set of culture conditions result in the differentiation of pericytes along a mesenchymal lineage forming bone muscle cells adipocytes chondroc...Tue, 18 May 2010 06:29:37 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5225Method to Produce Immunostimulatory Proteins and Tether Them to the Membrane of Enveloped Virus Vaccineshttp://wayne.technologypublisher.com/technology/5224Detailed Description Wayne State University researchers have developed a method to produce immunostimulatory cytokine proteins and tether them to the membrane of enveloped virus vaccines produced in cell culture. In vivo results to date indicate that this technology improves vaccine efficacy. Cytokines as soluble proteins have proven to be effective as adjuvants for experimental viral vaccines since they boost immune responses induce T cytotoxic cells and shift Th2 to Th1 responses. However there are limitations in formulations currently used to coadminister soluble cytokines: 1.It is d...Tue, 18 May 2010 06:29:37 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5224Hox B4http://wayne.technologypublisher.com/technology/5223Tue, 18 May 2010 06:29:36 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5223Visual Prostheses Based Upon Fiber-Optic Uncaging of Neurotransmitter Substanceshttp://wayne.technologypublisher.com/technology/5221Detailed Description A fiber optic cable may also be used to deliver light. The drug delivery system selectively delivers drugs to various types of neurological cells. In operation a solution of photoactivatable neuro-active drug is delivered to a pre-selected area in vivo and photoactivated in the solution at the pre-selected area to stimulate neurological tissue. The neuro-active drug may be either an agonist or an antagonist of neuronal activity. File Number: 00-496 Tue, 18 May 2010 06:29:34 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5221Functional Improvements in Fahr Diseasehttp://wayne.technologypublisher.com/technology/5220Tue, 18 May 2010 06:29:33 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5220Mannich Bases of Conjugated Styryl Ketoneshttp://wayne.technologypublisher.com/technology/5219Detailed Description Human infectious diseases caused by fungi have increased markedly during the past 10 years due mainly to advances in medical care that involve prolonged immune suppression increased use of cytotoxic drugs in cancer chemotherapy and the advent of AIDS. As a result organisms such as Candida albicans have become opportunistic pathogens capable of causing severe systemic infection. Consequently as high as 10% of hospital-acquired bloodstream infections are currently caused by fungi yet there have been few major improvements in the treatment and management of fungal in...Tue, 18 May 2010 06:29:33 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5219Establishment of a Prostate Carcinoma Bone Tumor Model in Micehttp://wayne.technologypublisher.com/technology/5218Tue, 18 May 2010 06:29:32 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5218Establishment of a Metastatic Prostate Carcinoma Tumor Model in Micehttp://wayne.technologypublisher.com/technology/5217Tue, 18 May 2010 06:29:32 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5217Establishment of a New Renal Cell Carcinoma Cell Line and a New Experimental Renal Tumor Modelhttp://wayne.technologypublisher.com/technology/5216Tue, 18 May 2010 06:29:31 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5216Novel Mammalian Putative Phosphatidylinositol-4-Phosphate-5-Kinasehttp://wayne.technologypublisher.com/technology/5214Tue, 18 May 2010 06:29:30 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5214Novel Prenyl Transferase Inhibitorshttp://wayne.technologypublisher.com/technology/5213Tue, 18 May 2010 06:29:30 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5213Method For Treating and/or Imaging Breast Cancer Using Radioactive Iodinehttp://wayne.technologypublisher.com/technology/5211Tue, 18 May 2010 06:29:28 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5211Programmable Antisiphon Shunt System (P-A-S-S)http://wayne.technologypublisher.com/technology/5209Tue, 18 May 2010 06:29:28 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5209DNA Molecule Encoding the B3 Adrenegic Receptorhttp://wayne.technologypublisher.com/technology/5208Tue, 18 May 2010 06:29:27 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5208Fluorescence-Based Assay for Demethylationhttp://wayne.technologypublisher.com/technology/5197Detailed Description WSU researchers have developed a fluorescence-based assay for the dealkylation activity of the non-heme iron (II) a-ketoglutarate-dependent dioxygenase family of enzymes. This assay uses formaldehyde dehydrogenase to convert formaldehyde to formic acid and monitors the creation of an NADH analog using fluorescence. The technology is a great improvement over the existing assays for DNA demethylation in that is continuous rapid and does not require radioactively labeled material. Additionally this assay may also be utilized to study the demethylation of histones. This...Thu, 13 May 2010 12:29:49 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5197New Technology of Production of Properly Folded Proteinhttp://wayne.technologypublisher.com/technology/5196This invention is a new protein transduction method for efficient delivery of exogenous proteins into mammalian cells. In contrast to known protein transduction methods, this new approach has the capability of targeting transduced proteins to different cellular compartments, as well as protecting the proteins from degradation by cellular proteases. The reagent for delivery of the proteins is composed of cationic agents, lipids and enhancer in a carrier. The Approach uses bacteria to produce recombinant proteins that are then modified with the reagent and delivered into mammalian cells....Thu, 13 May 2010 12:29:46 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5196Novel Biosensor Based on Parylene Cantilevershttp://wayne.technologypublisher.com/technology/5194 A Wayne State University researcher has developed a novel biosensor for DNA and protein microarray applications as well as lab-on-a-chip assays. The biosensor is composed of a micro-scale cantilever made of a polymer material with a modulus of elasticity significantly less than cantilever-based biosensors utilizing silicon nitride. Biosensors based on microfabricated cantilevers have attracted many interests in recent years. These sensors utilize the fact that when biochemical molecules (DNA antibody etc.) selectively bind to one side of the cantilever the surface stress induced will...Thu, 13 May 2010 12:29:43 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5194Austenitic (Non-Magnetic) Structural Steelhttp://wayne.technologypublisher.com/technology/5193Wayne State University research has yielded both a novel composition and a lower cost processing technique for the creation of austenitic non-magnetic structural steel. This steel has advantages that include a high work hardening rate, good corrosion resistance, combination of strength and ductility and good creep resistance. Use of this steel in energy generation devices will reduce magnetic permeability and thus reduce power loss. Commercial Applications • Naval structures and ship construction• Petrochemical and food processing industries• Energy generation devices Competitive Adv...Thu, 13 May 2010 12:29:42 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5193Pulsed Magnetic Field Anti-Inflammatory Devicehttp://wayne.technologypublisher.com/technology/5192Detailed Description Wayne State University and University of Michigan researchers have developed methods and devices which employ the use of electrical and magnetic fields to mitigate cellular responses to inflammation. Via the application of certain electric or magnetic fields changes and conversions of cell types are achieved along with modification of the physiological function of these cells thereby yielding a therapeutic effect. This approach affects neutrophils macrophages lymphocytes platelets and retinal cells and thus has the potential to provide therapeutic benefit to many di...Thu, 13 May 2010 12:29:41 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5192Hyperaccumulation of Arsenic in S. Cerevisiaehttp://wayne.technologypublisher.com/technology/5190Detailed Description WSU faculty developed an innovative biological technology that has promise to cost-effectively remove arsenic from drinking water. The technology employs the use of a genetically engineered strain of yeast with the ability to hyper-accumulate arsenic without releasing the arsenic back into the environment. The yeast is being optimized for arsenic accumulation the next step will be the development of bioreactors to remove arsenic from natural groundwater supplies. While federal legislation is still in flux regarding the implementation date for new maximum contaminant...Thu, 13 May 2010 12:29:40 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5190Broad Temperature Range MIS Hydrogen Sensorshttp://wayne.technologypublisher.com/technology/5187Thu, 13 May 2010 12:29:39 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5187A High Efficiency Booster for Automotive and Other Applicationshttp://wayne.technologypublisher.com/technology/5186 WSU faculty developed a high efficiency booster useful in devices where the gas turbine is the primary source of power and in hybrid automotive engines. Boosters are currently used in hybrid automotive engines or in stationary plants for the purpose of increasing the power output of the gas turbine. It is generally accepted that a good power producing system has reasonably high thermal efficiency consistent with economical environmental and other constraints. However current technology does not meet these goals since it provides only limited power output and thus decreased fuel e...Thu, 13 May 2010 12:29:38 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5186Magnetic Resonance Force Microscopy for Molecular Imaginghttp://wayne.technologypublisher.com/technology/5184Detailed Description Magnetic Resonance Force Microscopy (MRFM) is an emerging technology that combines the strengths of magnetic resonance and force microscopy to achieve high resolution three-dimensional sub-surface imaging of a test substance. WSU researchers have adapted and refined MRFM to study biological systems such as isolated cells sub-cellular organelles and other sub-cellular structures or cellular receptors and proteins at resolutions ranging from 1 micron to 1 angstrom. MRFM has the potential to significantly impact biomedical research and biotechnology including the poten...Thu, 13 May 2010 12:29:37 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5184High Gain Infrared Collector and Data Nodehttp://wayne.technologypublisher.com/technology/5183An infrared collector employs a concentrator formed of a plurality of spatially related gradient-indexed (GRIN) lenses and a photo detector interconnected by optical fibers. Since the GRIN lenses are arranged on a hemispherical shell the concentrator is relatively insensitive to the direction of the incoming infrared radiation. Optical fibers are used to connect the GRIN lenses to a photo detector where assembly is simplified. Commercial Applications • Infrared data networks Competitive Advantages • Infrared detector in the collector has a size that is significantly smaller than tho...Thu, 13 May 2010 12:29:37 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5183Biologically active ATP-Analogs for tagging phosphoproteinshttp://wayne.technologypublisher.com/technology/5174 A novel Photo Cross Linking Assay (PCLA) for targeting protein phosphorylation Protein phosphorylation catalyzed by kinases and phosphatases act at critical control points that regulates many cellular processes. This central role makes them an attractive target for identifying largely untapped and important biomarkers for disease diagnostics. Understanding which proteins interact in a given pathway is an important step to aid in the discovery of therapeutics. Despite the development of a variety of innovative new technologies, dissecting the phosphorylation cascades that regulates cellular ac...Tue, 11 May 2010 11:52:48 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5174Ultra-Sensitive Piezoresistive Accelerometer Based on Decoupled Piezoresistorshttp://wayne.technologypublisher.com/technology/5172Ultra-sensitive piezoresistive accelerometer that has advantages over traditional piezoresistive accelerometers in both the sensitivity and minimum detectable acceleration.Wayne State University researchers have developed an ultra-sensitive piezoresistive accelerometer that has advantages over traditional piezoresistive accelerometers in both the sensitivity and minimum detectable acceleration. Traditional piezoresistive accelerometers face challenges in applications where high bandwidth and high resolution are required simultaneously such as respiratory sound monitoring. Commercial Applicatio...Tue, 11 May 2010 11:52:47 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5172Microfluidic Particle Concentration and Separatorhttp://wayne.technologypublisher.com/technology/5170Researchers at the Wayne State University Smart Sensors and Integrated Microsystems (SSIM) laboratory have developed a micro-scale concentrator and separator applicable to several microfluidic applications. Initially the device was developed to concentrate and separate bacteria from other impurities to test water quality however the micro separator could have much broader applicability. The device and its fabrication method are unique. The device is composed of a large array of identical flow units arranged in a stagger and cascade fashion. As fluid is introduced to the system and accelerated ...Tue, 11 May 2010 11:52:45 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5170Development of TiO2 Anatase Thin Films Grown by Pulsed DC Magnetron Reactive Sputtering for Device Applicationshttp://wayne.technologypublisher.com/technology/5169WSU researchers have developed a novel procedure for creating Titanium Dioxide (TiO2) thin films using anatase material. Procedure uses TiO2 thin film with single phase a textured material and reproducible with different thickness on amorphous and crystalline substrates. Anatase is attracting much interest for its unique properties and has valuable properties such as high refractive index excellent transmittance in the visible and near-IR frequency and high chemical stability.The anatase material developed at the Wayne State University Smart Sensors and Integrated Microsystems laboratory (SSIM...Tue, 11 May 2010 11:52:44 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5169Self Cleaning Transparent Material Structure and its Fabrication Methodshttp://wayne.technologypublisher.com/technology/5168 A Wayne State University Professor has developed a material with unique self-cleaning properties that may serve a number of applications from self-cleaning automobile windshields, eyeglasses and optics to laboratory glassware, mirrors and sensors. Highly water-repellant materials (also known as Super Hydrophobic Surfaces) have been created and employed in a number of applications. However their widespread use to date has been hampered by the fact that such materials are generally non-transparent. As such these materials have not been suitable for windows windshields, camera lenses and...Tue, 11 May 2010 11:52:44 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5168SIRT2 Antibodyhttp://wayne.technologypublisher.com/technology/5167Tue, 11 May 2010 11:52:44 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5167Novel Method of Making 3-Dimensional Neural Probeshttp://wayne.technologypublisher.com/technology/5161Fri, 07 May 2010 12:26:29 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5161Effect of Natural and Synthetic Antioxidants on the Oxidative Stability of Biodieselhttp://wayne.technologypublisher.com/technology/5159Researchers at WSU’s National Biofuels Energy Laboratory have identified antioxidant additives for biodiesel fuel made from a variety of feedstock that provide advantages to current technologies. A significant problem associated with the commercial acceptance of biodiesel fuel is poor oxidative stability. The presence of high levels of unsaturated fatty acid methyl esters (FAME) makes biodiesel very susceptible to oxidation as compared to petroleum diesel. Oxidative processes can lead to the formation of insolubles which can potentially plug fuel filters and injection systems. The increased ac...Fri, 07 May 2010 12:26:28 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5159New Vehicle Roof Interior Design Concepts for Occupant Neck Protection During Rollover Crasheshttp://wayne.technologypublisher.com/technology/5158Researchers at the Bioengineering Center at WSU have developed an interior roof design that reduces the coefficient of friction (COF) between the head and the roof or reduces the COF between the padding and its supporting structure. Rollover crashes are the most hazardous crashes to the human cervical spine. It has been reported that the neck is the third most commonly injured body region during rollovers following the head and thorax and often leads to permanent disabilities. Currently vehicle interior roofs or headliners are not designed to reduce the risk of neck injuries in rollover accide...Fri, 07 May 2010 12:26:27 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5158Fabrication Methods for Anti-Reflection Surface on Transparent Materialshttp://wayne.technologypublisher.com/technology/5155Development of a fabrication method that uses optical nanostructures as artificial materials that match refractive indices of a wide range of transparent substrates. The resulting surface is optically transparent and exhibits qualities required to see images and text clearly on an electronic display screen in a wide variety of light conditions. Electronic display screens are difficult to see when light reflects off their surface. Glare caused from reflected light reduces the quality of displayed text and images on screens made of glass or plastic. Currently anti-reflection (AR) screen...Fri, 07 May 2010 12:26:26 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5155Microvascular Pericytes are Adult Pluripotential Stem Cellshttp://wayne.technologypublisher.com/technology/5154Detailed Description The existence of multipotent stem cells within the adult brain has been debated for some time. While the identity of this cell has been unknown it is clear that stem cells reside in specialized tissue (subventricular zone and subgranular zone) and that local microenvironments regulate their differentiation and self-renewal. WSU researchers have identified capillary pericytes as possessing pluripotent stem cell capability. One set of culture conditions result in the differentiation of pericytes along a mesenchymal lineage forming bone muscle cells adipocytes chondro...Fri, 07 May 2010 12:26:25 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5154Nanometer-Sized Drug Delivery Devices (Nanoparticles) that Demonstrate High Encapsulation Efficiency and Sustained Release of Water-Soluble Drugs and their Preparationhttp://wayne.technologypublisher.com/technology/5153WSU researchers have developed a nanoparticle formulation for the encapsulation of hydrophilic drugs with high efficiency. Encapsulation efficiency close to 100% has been achieved. Further these nanoparticles demonstrate sustained release of hydrophilic drugs over a period of weeks (~60-80% of encapsulated drug released over a period of 4 weeks). As a comparison published studies that investigate the use of other state of the art nanoparticles withwater-soluble drugs report sustained release only over a period of few hours. Additionally due to high surface area afforded by nanoparticle...Fri, 07 May 2010 12:26:25 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5153Antibodies to a Novel Cell Cycle and Apoptosis Regulatory Protein (CARP) -1http://wayne.technologypublisher.com/technology/5152 Retinoic acid and its synthetic derivatives participate in many biological processes including development cellular proliferation and differentiation. Retinoids mediate their actions by binding to the nuclear retinoic acid receptors and retinoid X receptors. Wayne State University researchers found that retinoid induced cell cycle arrest and apoptosis in several human breast carcinoma cell lines is independent of tumor suppressor p53 and estrogen receptor status via an undefined mechanism. This led to the identification of a novel cDNA which encodes a 130 Kda protein referred to as CA...Fri, 07 May 2010 12:26:25 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5152Derivation of Molecular Targets of Cancer and Aging Using Cellular Immortalization-Specific Gene-Expressionhttp://wayne.technologypublisher.com/technology/5151Fri, 07 May 2010 12:26:24 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5151An In Vitro Model System for Studying Development of Human Preneoplastic Breast Diseasehttp://wayne.technologypublisher.com/technology/5149Wayne State University researchers have developed a novel model/assay system that recapitulates in vitro the in vivo processes that lead to breast cancer development and progression from preneoplastic tissue. This model is the first that demonstrates in vitro the de novo development and neoplastic conversion of functional alveolar units. Advantages of this model include the fact that it requires only about 7 days for alveolar morphogenesis to occur compared to 8-10 weeks in vivo. This permits the use of this system for relatively high throughput drug screening. In this model preneoplas...Fri, 07 May 2010 12:26:23 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5149Gene for Chicken Interleukin 15...http://wayne.technologypublisher.com/technology/5147 Detailed Description WSU researchers have cloned and patented chicken IL-2 and related avian lymphokines for use as avian vaccine adjuvants. The inventors have shown experimentally that chicken IL-2 can enhance vaccine effectiveness in chickens. Future research to further enable this technology will likely include optimization of delivery methods. IL-2 has a short serum half-life and for maximum efficacy must be attached to or closely associated with the vaccine antigen(s). Various studies have utilized chicken IL-2 fused to antigen expressed by viral vaccine vectors and expressed in D...Fri, 07 May 2010 12:26:22 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5147New Immunotherapies for Cancerhttp://wayne.technologypublisher.com/technology/5138Thu, 06 May 2010 08:14:36 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5138Tumor Targeting by Small Molecule Therapeutics for a Proton-Coupled Folate Transporter (PCFT)http://wayne.technologypublisher.com/technology/5134Thu, 06 May 2010 08:14:33 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5134Galectin-3 Single Nucleotide Polymorphism rs4644 Predicts Human Cancer Risk Associated with Racial Disparityhttp://wayne.technologypublisher.com/technology/5131Thu, 06 May 2010 08:14:32 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5131A Diagnostic Marker for Matrix Metalloprotease (MMP)-2 and -9 Activity in Cancer Tissuehttp://wayne.technologypublisher.com/technology/5130Thu, 06 May 2010 08:14:31 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5130Improved pDMI Inhaler Formulationshttp://wayne.technologypublisher.com/technology/5129Thu, 06 May 2010 08:14:31 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5129Sub-monolayer detection with surface selective vibrational spectroscopyhttp://wayne.technologypublisher.com/technology/5128Thu, 06 May 2010 08:14:30 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5128New Technology of Studying Protein Structure/Folding Functions in Living Mammalian Cellshttp://wayne.technologypublisher.com/technology/5127 This invention is a new protein transduction method for efficient delivery of exogenous proteins into mammalian cells. In contrast to known protein transduction methods, this new approach has the capability of targeting transduced proteins to different cellular compartments, as well as protecting the proteins from degradation by cellular proteases. The reagent for delivery of the proteins is composed of cationic agents, lipids and enhancer in a carrier. The Approach uses bacteria to produce recombinant proteins that are then modified with the reagent and delivered into mammalian cells...Thu, 06 May 2010 08:14:29 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5127Stool/Tissue Preservation Devicehttp://wayne.technologypublisher.com/technology/5126 WSU inventors have designed devices that enable small pieces of human tissue or stool to be rapidly immersed and preserved at room temperature in toxic preservatives without exposing the end user to the toxicants. Samples contained in the device can be safely stored or used for biochemical, molecular, and structural analysis. The device design makes them very easy and safe to operate. They can be used at home, hospital, or out in the field for forensic sample collection without the need for refrigeration. Furthermore, the provider/manufacture of the device has the flexibility of using...Thu, 06 May 2010 08:14:29 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5126Folate Receptor Targeted Therapeutics for Cancerhttp://wayne.technologypublisher.com/technology/5125Collaborative researchers at WSU and Duquesne University have developed a series of novel folate analogs that show selective toxicity toward tumor cells expressing high levels of the surface protein folate receptor. Typically, normal cells express low levels of folate receptors or such receptors exhibit apical localization and are not exposed to the blood. In additional to the folate receptor selectivity, these compounds are potent inhibitors of glycinamide transformylase (GARTFase), a purine nucleotide biosynthetic enzyme. This is the first description of a compound exhibiting both ch...Thu, 06 May 2010 08:14:29 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5125Imaging Tandem Mass Spectrometry: Reduction to Practicehttp://wayne.technologypublisher.com/technology/5124 Currently, tandem mass spectrometry is typically performed by selecting a single mass peak in a time of flight or quadrupole mass spectrometer, which is then fragmented through collision, after which the products are mass-selected in a quadrupole or similar secondary mass spectrometer. A Wayne State University researcher has developed an alternative approach which records the full 2-D tandem mass spectrum at once, revealing the correlations between the mass speaks formed in the first and second step. Velocity map imaging is coupled with pulsed electric deflection in a reflectron confi...Thu, 06 May 2010 08:14:28 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5124Novel Dual and Triple Acting CNS Compounds with Potential as Antidepressants, Medications for Attention Deficit Disorders and other Related Neuro-disordershttp://wayne.technologypublisher.com/technology/5118 Wayne State University researchers have identified compounds with a unique molecular template exhibiting reuptake inhibition activity for both at the norepinephrine and serotonin transporters in the CNS. In addition, some of these molecules also exhibit triple reuptake activity for the dopamine, serotonin and norepinephrine transporters. These compounds have shown impressive dual and triple uptake inhibition activity in vitro, have exhibited in vivo antidepressant activity in forced swimming test model in both mice and rats. Lead compounds will be tested in additional in vivo models, ...Thu, 06 May 2010 08:14:25 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5118Designer Aminoglycosideshttp://wayne.technologypublisher.com/technology/5117Wayne State University researchers have synthesized a series of novel aminoglycoside antibiotics that have shown enhanced antibacterial activity, low susceptibility to existing resistance mechanisms and low toxicity when compared to currently marketed aminoglycosides. Aminoglycoside antibiotics have been used against a wide variety of bacterial infections caused by Gram-positive and Gram-negative bacteria. The activity of the aminoglycosides is due to binding to bacterial RNA. Currently marketed aminoglycoside antibiotics are indicated for treatment of serious bacterial infections, but...Thu, 06 May 2010 08:14:24 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5117CNS Compounds Specific for the Monoamine Transporter Systemshttp://wayne.technologypublisher.com/technology/5116The dopamine transporter (DAT) plays an important role in pathophysiological processes in the central nervous system. In cocaine addiction, binding of cocaine to the DAT and consequent blockage of dopamine uptake appears to be related to the reinforcing properties of the drug. Also associated with the transport function is concentration of neurotoxic chemicals in dopaminergic neurons which is implicated in Parkinson’s disease. Potent, yet selective ligands for the DAT have potential for in vivo monitoring of primary targets of cocaine in the brain, for the characterization of cocaine b...Thu, 06 May 2010 08:14:24 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5116Novel Hybrid Series of Compound Derived from 2-Aminotetralin and Piperazine Based Derivatives: Characterization for D1, D2, D3, D4 and other Serotonin Receptor Subtypes Bindinghttp://wayne.technologypublisher.com/technology/5115 A series of compounds derived from 2-aminotetralin and piperazine fragments have been synthesized, which exhibit high CNS activity in vivo and in vitro. Some of the selected lead compounds have exhibited potent in vivo activity in a Parkinson’s disease animal model with long extended duration of action. In particular, these compounds show high D3 receptor affinity and/or high D3/D2 selectivity. In addition to the potential therapeutic treatment of Parkinson’s disease and depression, these novel compounds have possible application in the treatment of a number of other neurological diso...Thu, 06 May 2010 08:14:23 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5115Dynamic Bandwidth Allocation Algorithm for Automated Video Surveillance Systemshttp://wayne.technologypublisher.com/technology/5081Technology Overview Wayne State researchers have addressed the scalability-cost and power consumption problems of large-scale surveillance systems by developing an optimal bandwidth allocation algorithm, which controls the transfer rates of various video sources. With dynamic bandwidth allocation, the surveillance coverage can be widened as much as possible throughout the site without greatly increasing the required resources and thus the overall system cost. The algorithm considers the potential threat level, placement of video sources, location importance, site map, and rate-accurac...Thu, 29 Apr 2010 11:44:21 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/5081Volatile Thermally Stable Transition Metal Precursors for Thin Film Growthhttp://wayne.technologypublisher.com/technology/4988Fri, 23 Apr 2010 12:54:03 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/4988Integrated Optical Polarizer for Silicon-on-Insulator Waveguideshttp://wayne.technologypublisher.com/technology/4987Integrated optics based on silicon-on-insulator platforms are developing extremely fast due to technological compatibility with complementary metal-oxide-semiconductor (CMOS) fabrication process widely accepted in microelectronics.  Wayne State researchers have developed a technology which generates an integrated optical polarizer for high index contrast SOl waveguides, which operates through resonant coupling of TM-polarized guided mode to a high-index mode supported by a nanoscale metal dielectric multilayer, such as gap plasmon-polariton.  This new technology of several nano-scale metal-die...Fri, 23 Apr 2010 12:54:02 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/49873D Soundscapinghttp://wayne.technologypublisher.com/technology/4882 Researchers at WSU have developed a 3D Soundscaping technology that enables one to take sound measurements to a new level by locating sound sources, visualize their resultant sound pressure fields in 3D space. In traditional sound sensing applications, sound is measured using microphones and sound pressure levels and spectra are measured at survey locations. It is suitable for all types of sounds including continuous, transient, random, harmonic, impulsive, narrow- and broadband sounds. All this is done by using four microphones, thus significantly cutting the overall costs. Moreover, this n...Tue, 06 Apr 2010 08:36:16 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/4882Omni-Directional Angular Acceleration Reduction Helmethttp://wayne.technologypublisher.com/technology/4767Wayne State researchers have designed a new device to reduce the head angular acceleration of the helmet wearer during blunt impact. This technology introduces a helmet shell design which rotates with respect to head by the insertion of a thin layer of elastically or plastically yielding material between the outer and inner shells, depending on the type of helmet.  Current helmet technology utilizes a double shell technology with the outer shell rotating in respect to the inner shell. Due to the restriction of rotation about only one axis and the lack of control of stopping the outer shell of ...Fri, 19 Mar 2010 07:22:16 GMTttoinfo@wayne.eduhttp://wayne.technologypublisher.com/technology/4767