Search Results - "Life Science" and "Diseases" and "Infectious Disease"




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Activated T Cells and Activated T Cells Armed with BiSpecific Antibodies Directed at Cancer Antigens are Poor Responders to Alloantigens May Help Engraftment and Improve Anti-Tumor Effects
BackgroundThe treatment of hematologic malignancies with allogeneic stem cell transplant is limited by the numbers of allogeneic donors. Umbilical cord blood stem transplants have been an important alternative source of hematopoietic stem cells. However, failure or delayed engraftment remains the critical barrier to the success of the transplants...
Published: 8/3/2017   |   Inventor(s): Lawrence Lum
Keywords(s): Anti-cancer
Category(s): Life Science, Therapeutics, Diseases, Infectious disease
Antibacterial activity of natural compounds and their synthetic analogue: A potential new antibiotic with potent activity against multiple drug resistant bacterial pathogens
Our researchers have developed novel compounds that are potential antibiotics useful for treatment against the deadly bacteria MRSA (methicillin-resistant Staphylococcus aureus), VRE (vancomycin-resistant Enterococcus faecium), and several other well-known common infectious agents.Background & Unmet Need:Before antibiotics became available in t...
Published: 5/12/2015   |   Inventor(s): Fazlul Sarkar, Hossein Salimnia, Subhash Padhye, Bernhard Biersack
Keywords(s): Analog or Analogue, Antibiotics, Anti-infective, Anti-microbial, Disease
Category(s): Biologicals, Diseases, Infectious disease, Life Science, Therapeutics
Using Flagellin to Prevent and to Treat Inflammation Associated Gram Negative Bacterial Infection
This technology provides a new method for treating inflammatory diseases by using a Gram negative bacterial component that results in increased tolerance and immunity. Background & Unmet Need: Despite advances of modern medicine, bacterial sepsis remains one of the major threats to human health worldwide. In the US alone, it affects approxima...
Published: 5/18/2010   |   Inventor(s): Fu-Shin Yu, Ashok Kumar, Jing Zhang, Linda Hazlett
Keywords(s): Anti-microbial, Asthma
Category(s): Therapeutics, Diseases, Life Science, Infectious disease
Designer Aminoglycosides
Wayne State University researchers have synthesized a series of novel aminoglycoside antibiotics that have shown enhanced antibacterial activity, low susceptibility to existing resistance mechanisms and low toxicity when compared to currently marketed aminoglycosides. Aminoglycoside antibiotics have been used against a wide variety of bacteria...
Published: 5/6/2010   |   Inventor(s): Shahriar Mobashery, Lakshmi Kotra, Jalal Haddad
Keywords(s): Antibiotics
Category(s): Therapeutics, Life Science, Small molecule, Diseases, Infectious disease