Search Results - Protein%2fpeptides

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Fc-folate conjugate for the treatment of triple negative breast cancer

Approximately 13% of women in the United States will develop breast cancer according to the American Cancer Society. That makes breast cancer the second leading cause of cancer death in women right behind lung cancer. Triple negative breast cancer (TNBC) represents about 10 – 20% of all breast cancers. Triple negative refers to cancer cells...

Published: 12/7/2022 | Inventor(s): Cecilia Speyer

Keywords(s): Anti-cancer, Breast Cancer, Cancer, Cancer Therapies

Category(s): Antibodies, Assays, Biology, Biomedical, Chemical Processing/Synthesis, Diseases, Drug Delivery, Life Science, Oncology, Protein/peptides, Receptors/targets, Small molecule, Therapeutics

Disulfide by Design 2.0: A web-based tool for disulfide engineering in proteins

Background:Immunoinformatics employs a computer-driven approach to identifying fragments of the target pathogen that would provide a suitable vaccine, avoiding potential safety concerns from the more traditional approach of using whole pathogens. Immunoinformatics now plays a crucial role in vaccine design, immunodiagnostic development, and antibody...

Published: 4/18/2022 | Inventor(s): Alan Dombkowski, Douglas Craig

Keywords(s): Coronavirus, COVID-19

Category(s): Life Science, Software, Simulation & Modeling, Research tools, Computer Software, Protein/peptides

Tx2 metal-binding tag for purification and identification of recombinant proteins

Tx2 Metal-Binding Tag for Purification and Identification of Recombinant Proteins WSU Tech#: 11-1058Technology Summary: The technology is a new method of protein purification similar to the principles behind that of a histidine and Ni column system. The new technology uses a different amino acid sequence for generating a metal-binding cluster:T: “H...

Published: 2/28/2022 | Inventor(s): Jian-Ping Jin

Keywords(s): Assay, Biotechnology, Process, Protein, Reagents, Tool

Category(s): Life Science, Research tools, Protein/peptides

A Gene Knockout Mouse Model to Study Lung Disease and a Lung Disease Drug Target

Our researchers have created a gene knockout mouse model that lacks the cytochrome c oxidase subunit IV-2 in order to study the gene’s effects on controlling asthma. Background & Unmeet Need: Asthma is an inflammatory disease of the airways that affects 155 million people of all ages worldwide. Cytochome c oxidase (CcO) is a multi-subunit...

Published: 3/3/2022 | Inventor(s): Maik Huettemann, Lawrence Grossman, David Bassett

Keywords(s): Asthma, Disease, Drug Target, Gene, Knock-out, Lung, Mouse Model

Category(s): Animal models, Biological materials, Life Science, Research tools, Protein/peptides

Topical treatment with TGFbeta3 to facilitate skin and corneal wound healing in diabetic patients

Background: Diabetes affects approximately 170 million people worldwide, including 20.8 million in the USA, and by 2030 these numbers are projected to double. Diabetics often experience slow or limited wound healing. Slow wound healing allows longer time for the development of infections and can contribute to the formation of bed sores and ulcers....

Published: 9/16/2019 | Inventor(s): Fu-Shin Yu

Keywords(s): Diabetes

Category(s): Medical, Biologicals, Biomedical, Drug Discovery, Metabolic disorders, Protein/peptides, Therapeutics, Life Science

Peptide Antimicrobial

In vivo Display Technology for the Isolation of Antimicrobial Peptides Professor Philip R. Cunningham, Ph.D. Department of Biological Sciences @ Wayne State University Interest in peptides as antimicrobial agents has increased dramatically in recent years, driven primarily by the development of new technologies for producing, screening and analyzing...

Published: 12/7/2022 | Inventor(s): Philip Cunningham, Wes Colangelo

Keywords(s):

Category(s): Pharmaceuticals, Life Science, Research tools, Assays, Biological materials, Protein/peptides