http://wayne.technologypublisher.comBe the first to know about the latest inventions and technologies available from Wayne State Universityen-USFri, 26 Jun 2026 18:21:58 GMTTue, 16 Jun 2026 17:03:16 GMThttp://blogs.law.harvard.edu/tech/rssttoinfo@wayne.eduCopyright 2026, Wayne State University15-1272https://wayne.technologypublisher.com/technology/61744Selective C4-modified SAHA analogs inhibit HDAC6 and HDAC8 enzymes for targeted therapeutic applications. Technology Summary Histone deacetylase (HDAC) proteins are key players in cancer progression and have emerged recently as targets for anti-cancer drugs. WSU researchers have synthesized a variety of small molecule HDAC inhibitors and evaluated their potencies. This technology involves the design, synthesis, and characterization of C4-modified suberoylanilide hydroxamic acid (SAHA) analogs that selectively inhibit histone deacetylase enzymes HDAC6 and HDAC8. These...Tue, 16 Jun 2026 17:03:16 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/6174415-1263https://wayne.technologypublisher.com/technology/61742Tue, 16 Jun 2026 16:30:29 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/6174217-1404https://wayne.technologypublisher.com/technology/61359Tue, 12 May 2026 15:53:59 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/6135922-1697https://wayne.technologypublisher.com/technology/61216Fri, 24 Apr 2026 12:54:45 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/6121625-1808https://wayne.technologypublisher.com/technology/61212Fri, 24 Apr 2026 09:41:17 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/6121217-1460https://wayne.technologypublisher.com/technology/61176Fri, 17 Apr 2026 10:34:57 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/6117622-1665https://wayne.technologypublisher.com/technology/61085 Description: This invention is a portable, integrated metal additive-deformation-machining system designed for high-quality prototype manufacturing and efficient in-field tooling repair. The Unified Additive Deformation and Machining (ADM) technology combines metal deposition, thermal-mechanical deformation, and precision machining into a single coordinated platform. This patented process enables microstructure refinement and superior mechanical properties in repaired or fabricated metal parts. The current project focuses on miniaturizing this laboratory-validated system into a compact, por...Wed, 08 Apr 2026 08:19:49 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/6108523-1723https://wayne.technologypublisher.com/technology/61079Tue, 07 Apr 2026 08:40:25 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/6107924-1749https://wayne.technologypublisher.com/technology/59972Thu, 29 Jan 2026 13:37:59 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5997225-1803https://wayne.technologypublisher.com/technology/59949Tue, 27 Jan 2026 13:37:46 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5994916-1346https://wayne.technologypublisher.com/technology/59818Fri, 09 Jan 2026 09:43:29 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5981821-1627https://wayne.technologypublisher.com/technology/59817Fri, 09 Jan 2026 08:41:04 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5981724-1750https://wayne.technologypublisher.com/technology/59791A novel hydrophobically modified diglycolamide (DGA) sorbent on organosilica enables selective, efficient, and sustainable recovery of rare earth elements (REEs) from low-grade and waste sources. Technology Summary This technology features a modified diglycolamide ligand, notably N,N,N,N-Tetraoctyl Diglycolamide (TODGA), functionalized with hydrophobic alkane chains and immobilized on a swellable organosilica support to create a stable sorbent media. It selectively extracts heavy rare earth elements (HREEs) from complex acidic solutions such as coal fly ash, phosphate fertilizers, and e-wast...Tue, 06 Jan 2026 10:29:58 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5979124-1754https://wayne.technologypublisher.com/technology/59713Tue, 23 Dec 2025 04:36:16 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5971324-1756https://wayne.technologypublisher.com/technology/59624Mon, 15 Dec 2025 14:05:22 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5962424-1786https://wayne.technologypublisher.com/technology/59622Description: This innovative 3D imaging system uses time-of-flight measurement of photons with a conventional global shutter CMOS camera to generate accurate distance data converted into brightness levels. It includes a laser source, camera, delay generator, master trigger, and electronic control unit (ECU) which together capture and average multiple jittered frames to produce normalized intensity images. These images are calibrated to create high-precision 3D point clouds capable of detecting objects over 50 meters away. The design focuses on simplicity, cost-effectiveness, and scalability, ...Mon, 15 Dec 2025 13:46:19 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5962224-1765https://wayne.technologypublisher.com/technology/59069Thu, 06 Nov 2025 11:02:13 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5906925-1814https://wayne.technologypublisher.com/technology/59067Thu, 06 Nov 2025 09:31:02 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5906716-1356https://wayne.technologypublisher.com/technology/58983Tue, 28 Oct 2025 10:30:31 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5898323-1735https://wayne.technologypublisher.com/technology/58916Wed, 22 Oct 2025 12:02:52 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5891619-1517https://wayne.technologypublisher.com/technology/58478An enhanced image-guidance system that integrates ultrasound and photoacoustic into existing ablation systems to provide an enhanced image-guidance system for identification of cervical tissue changes during pregnancy and postpartum. Technology Summary Preterm delivery is a main cause of perinatal morbidity and mortality worldwide, which is associated with a significant healthcare cost spent on prematurity. Cervical remodeling during pregnancy is a critical process that can lead to complications such as preterm birth (PTB). This technology introduces a novel multi-parametric approach combin...Wed, 10 Sep 2025 13:25:01 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5847820-1610https://wayne.technologypublisher.com/technology/45146Tue, 19 Oct 2021 10:02:23 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/4514619-1516https://wayne.technologypublisher.com/technology/42500Wed, 02 Dec 2020 09:49:32 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/4250015-1264https://wayne.technologypublisher.com/technology/39713Wed, 29 Apr 2020 09:54:00 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/3971307-824https://wayne.technologypublisher.com/technology/37301Wed, 04 Dec 2019 12:23:07 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/3730106-789https://wayne.technologypublisher.com/technology/36288Tue, 17 Sep 2019 12:02:47 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/3628808-943https://wayne.technologypublisher.com/technology/25833Thu, 03 Aug 2017 08:51:08 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/2583313-1138https://wayne.technologypublisher.com/technology/13504Fri, 11 Oct 2013 08:07:14 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/1350412-1079https://wayne.technologypublisher.com/technology/12395Mon, 29 Apr 2013 10:33:19 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/1239509-939https://wayne.technologypublisher.com/technology/12392Technology Summary: Laser Spray Ionization (LSI) is a novel inlet ionization method for mass spectrometry invented at WSU which can be used to create predominately multiply charged ions from solid samples at atmospheric pressure. Unlike MALDI ionization methods which are typically limited to producing singly charged species for larger molecules, LSI produces ions similar to Electrospray Ionization (ESI) methods without the need for a solvent or voltage. With higher charged ions, LSI extends the mass range (m/z) for high MW analytes which is typically limited in high resolution mass spec instru...Fri, 26 Apr 2013 12:21:02 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/1239211-1004https://wayne.technologypublisher.com/technology/7051Mon, 02 May 2011 10:42:22 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/705104-684https://wayne.technologypublisher.com/technology/5167Tue, 11 May 2010 11:52:44 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/516707-858https://wayne.technologypublisher.com/technology/5130Thu, 06 May 2010 08:14:31 GMTttoinfo@wayne.eduhttps://wayne.technologypublisher.com/technology/5130