Search Results - %22Life+Science%22+and+%22Diagnostic%22

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ERK-Mediated Grb7 Phosphorylation: A Biomarker and Potential Therapeutic Target in Her2/Grb7 Amplified Cancers

This invention is a new bio-marker for breast and other cancers that have Her2 and Grb7 gene amplifications, thus providing a therapeutic intervention in Her2/Grb7 amplified cancers.Background40% of breast cancers, as well as several other cancer types, display increased activation of tyrosine kinases from the ErbB family, with Her2 found amplified...

Published: 3/12/2018 | Inventor(s): Guri Tzivion, Deborah Leicht, Alexander Kaplun, Stephen Ethier

Keywords(s): Biomarker, Biotechnology, Cancer, Cancer Therapies, Therapeutics

Category(s): Diagnostic, Life Science, Oncology

A method to identify patients at risk for subsequent stillbirth in the third trimester

A Method to Identify and Treat Patients at Risk for Stillbirth in the 3rd TrimesterWSU Tech#: 12-1113Technology Summary: This invention is a method of identifying patients at risk for subsequent stillbirth (only due to placental related disorder) in the third trimester using a maternal blood sample. A blood sample would be obtained at the beginning...

Published: 1/12/2022 | Inventor(s): Tinnakorn Chaiworapongsa, Roberto Romero, Sonia Hassan

Keywords(s):

Category(s): Medical, Diagnostic, Prenatal, Small molecule, Specialty compounds, Therapeutics, Life Science

Method For Treating and/or Imaging Breast Cancer Using Radioactive Iodine

This invention involves treating a breast cancer patient by the administration of a radioisotope of iodine in a dosage of between 5 and 50 milliCuries over the course of a day. The therapeutic composition is designed for mammary tissue uptake and includes an inorganic radioactive iodide salt (e.g., alkali metal, alkali earth or transition metal...

Published: 2/27/2022 | Inventor(s): James Rillema

Keywords(s): Anti-cancer, Breast Cancer, Cancer Therapies, Imaging, Therapeutics

Category(s): Therapeutics, Life Science, Oncology, Receptors/targets, Diagnostic, Imaging

SIRT2 Antibody

This technology is a novel rabbit antibody for SIRT2 ( Sirtuin 2) designed to follow human SIRT2 proteins in order to determine their role in gene regulation and apoptosis.Background & Unmet Need:The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress...

Published: 2/18/2022 | Inventor(s): Michael Tainsky, Sylvia Dryden

Keywords(s): Compound, Protein

Category(s): Diagnostic, Antibodies, Life Science, Research tools

Antibodies to a Novel Cell Cycle and Apoptosis Regulatory Protein (CARP) -1

Wayne State University researchers have identified a novel cDNA which encodes a pro-apoptotic protein called CARP-1 (Cell Cycle and Apoptosis Regulatory Protein-1), which is expressed in many cancer cell types including breast and colon carcinoma cells. This novel cDNA can be used as a diagnostic and prognostic tool for many types of cancer. Background...

Published: 2/8/2022 | Inventor(s): Arun Rishi, Joseph Fontana

Keywords(s): Antibody, Breast Cancer, Cancer, Drug Target

Category(s): Diagnostic, Life Science, Research tools, Antibodies

Derivation of Molecular Targets of Cancer and Aging Using Cellular Immortalization-Specific Gene-Expression

This technology identifies molecular targets required for immortalization, which is a trait spontaneously acquired by cancer cells. These targets may provide a potential means to intervene in the process of aging or cancer development. Background & Unmet Need: Recent efforts to develop improved methods for breast cancer detection, staging, and...

Published: 10/5/2018 | Inventor(s): Sorin Draghici, Olga Studitskaia, Michael Tainsky

Keywords(s): Cancer, Drug Target

Category(s): Diagnostic, Life Science, Oncology