Search Results - %22Life+Science%22+and+%22Research+Tools%22+and+%22Assays%22

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Translation Regulated (TR)-Mediated Gene Expression: Novel Expression and Reporter Vectors

Background: Often referred to as the crucial "drug discovery tool", cell based technology is one of the most significant sectors of pharmaceutical research and development. Of particular importance has been the development of information-rich cellular assays that determine drug candidate efficacy and safety (target identification, validation...

Published: 4/17/2022 | Inventor(s): Leon Carlock, Maria Cypher

Keywords(s): Animal Model, Anti-cancer, Cancer, Cancer risk, Cancer Therapies, Diagnostics, Imaging, Therapeutics

Category(s): Life Science, Diagnostics, Research tools, Assays, Cell lines, Oncology

Peptide Antimicrobial

In vivo Display Technology for the Isolation of Antimicrobial Peptides Professor Philip R. Cunningham, Ph.D. Department of Biological Sciences @ Wayne State University Interest in peptides as antimicrobial agents has increased dramatically in recent years, driven primarily by the development of new technologies for producing, screening and analyzing...

Published: 12/7/2022 | Inventor(s): Philip Cunningham, Wes Colangelo

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Category(s): Pharmaceuticals, Life Science, Research tools, Assays, Biological materials, Protein/peptides

Fluorescence-Based Assay for Demethylation

Detailed Description WSU researchers have developed a fluorescence-based assay for the dealkylation activity of the non-heme iron (II) a-ketoglutarate-dependent dioxygenase family of enzymes. This assay uses formaldehyde dehydrogenase to convert formaldehyde to formic acid and monitors the creation of an NADH analog using fluorescence. The technology...

Published: 11/26/2019 | Inventor(s): Ashok Bhagwat, Todd Roy

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Category(s): Assays, Life Science, Research tools

Biologically active ATP-Analogs for tagging phosphoproteins

A novel Photo Cross Linking Assay (PCLA) for targeting protein phosphorylation Protein phosphorylation catalyzed by kinases and phosphatases act at critical control points that regulates many cellular processes. This central role makes them an attractive target for identifying largely untapped and important biomarkers for disease diagnostics. Understanding...

Published: 11/11/2021 | Inventor(s): Mary Pflum

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Category(s): Chemicals, Life Science, Research tools, Assays, Reagents