Search Results - "Research Tools" and "Assays"




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"Generation of an affinity-purified rabbit anti-CREBH polyclonal antibody"
Generation of an Affinity-Purified Rabbit Anti-CREBH Polyclonal Antibody WSU Tech#: 15-1271 Technology Summary: CREBH (also called CREB3L3) is a stress-inducible metabolic regulator that plays key roles in hepatic lipolysis, fatty acid oxidation, gluconeogenesis, and lipogenesis. CREBH is critically involved in fatty liver disease and its assoc...
Published: 5/19/2017   |   Inventor(s): Kezhong Zhang
Keywords(s):  
Category(s): Research tools, Antibodies, Assays
Translation Regulated (TR)-Mediated Gene Expression: Novel Expression and Reporter Vectors
Background: Often referred to as the crucial "drug discovery tool", cell based technology is one of the most significant sectors of pharmaceutical research and development. Of particular importance has been the development of information-rich cellular assays that determine drug candidate efficacy and safety (target identification, valida...
Published: 8/14/2013   |   Inventor(s): Leon Carlock, Maria Cypher
Keywords(s): Animal Model, Anti-cancer, Cancer, Cancer risk, Cancer Therapies, Diagnostics, Imaging, Therapeutics
Category(s): Life Science, Diagnostics, Research tools, Assays, Cell lines
Peptide Antimicrobial
In vivo Display Technology for the Isolation of Antimicrobial Peptides Professor Philip R. Cunningham, Ph.D. Department of Biological Sciences @ Wayne State University Interest in peptides as antimicrobial agents has increased dramatically in recent years, driven primarily by the development of new technologies for producing, screening and analyz...
Published: 5/3/2011   |   Inventor(s): Philip Cunningham, Wes Colangelo
Keywords(s):  
Category(s): Pharmaceuticals, Life Science, Research tools, Assays, Biological materials, Protein/peptides
Fluorescence-Based Assay for Demethylation
Detailed Description WSU researchers have developed a fluorescence-based assay for the dealkylation activity of the non-heme iron (II) a-ketoglutarate-dependent dioxygenase family of enzymes. This assay uses formaldehyde dehydrogenase to convert formaldehyde to formic acid and monitors the creation of an NADH analog using fluorescence. The tech...
Published: 5/13/2010   |   Inventor(s): Ashok Bhagwat, Todd Roy
Keywords(s):  
Category(s): Assays, Life Science, Research tools
Biologically active ATP-Analogs for tagging phosphoproteins
A novel Photo Cross Linking Assay (PCLA) for targeting protein phosphorylation Protein phosphorylation catalyzed by kinases and phosphatases act at critical control points that regulates many cellular processes. This central role makes them an attractive target for identifying largely untapped and important biomarkers for disease diagnostics. Under...
Published: 5/11/2010   |   Inventor(s): Mary Pflum
Keywords(s): Assay, Biomarker, Protein
Category(s): Chemicals, Life Science, Research tools, Assays, Reagents
An In Vitro Model System for Studying Development of Human Preneoplastic Breast Disease
This technology is a novel model/assay system that recapitulates in vitro the in vivo processes that lead to breast cancer development and progression from preneoplastic tissue. This model is the first that demonstrates in vitro the de novo development and neoplastic conversion of functional alveolar units. Background & Unmet Need: Although ...
Published: 5/7/2010   |   Inventor(s): Malathy Shekhar, Larry Tait
Keywords(s): Assay, Breast Cancer
Category(s): Drug Discovery, Assays, Life Science, Oncology, Research tools, Diseases