Search Results - Animal models




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Generation of gp78 null mice
Generation of gp78 null mice WSU Tech#: 15-1291 Technology: Generation of the first preclinical experimental model system for gp78-/- C57BL/6 mice, which spontaneously develops age-related nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC), linking endoplasmic reticulum-associated degradation (ERAD) to hepatosteatosis, cirrhosis...
Published: 5/19/2017   |   Inventor(s): Avraham Raz, Andrei Golovko
Keywords(s):  
Category(s): Animal models, Biology, Biomedical, Biotechnology, Drug Delivery, Drug Discovery, Drug Screening, Genomics/Genetics, Life Science, Oncology, Research tools
Establishment of a Prostate Carcinoma Bone Tumor Model in Mice
This technology is a new tumorigenic cell line from the human prostate carcinoma cell line PC-3. These cell lines, known as PC-3/IF, when implanted in the femurs of nude mice, provide a xenograft tumor model of bone metastatic prostate carcinoma. The PC-3/IF cell lines are highly tumorigenic, with tumor cells replacing the marrow cells in the bon...
Published: 5/18/2010   |   Inventor(s): Gilda Hillman
Keywords(s): Animal Model, Prostate Cancer, Research Tool
Category(s): Animal models, Life Science, Research tools, Oncology, Diseases
Establishment of a Metastatic Prostate Carcinoma Tumor Model in Mice
This technology is a new tumorigenic cell line from the human prostate carcinoma cell line PC-3. These cell lines, known as PC-3/PI, are highly tumorigenic when implanted in the prostate of nude mice, providing a xenograft tumor model of prostate carcinoma. In this model, lymph node metastases form from the primary tumor, similar to what occurs i...
Published: 5/18/2010   |   Inventor(s): Gilda Hillman
Keywords(s): Animal Model, Cancer, Prostate Cancer, Research Tool
Category(s): Animal models, Life Science, Oncology, Research tools, Diseases
Establishment of a New Renal Cell Carcinoma Cell Line and a New Experimental Renal Tumor Model
This technology is a tumor cell line from a primary papillary renal cell carcinoma that, when implanted in the kidney of nude mice, provides a xenograft tumor model of human renal cell carcinoma. Background & Unmet Need: Renal cell carcinoma, which occurs in the parenchyma of the kidney, is the most common type of renal cancer, accounting for ...
Published: 5/18/2010   |   Inventor(s): Gilda Hillman
Keywords(s): Animal Model, Cancer, Research Tool
Category(s): Animal models, Life Science, Oncology, Research tools, Diseases