Search Results - Diagnostic




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ERK-Mediated Grb7 Phosphorylation: A Biomarker and Potential Therapeutic Target in Her2/Grb7 Amplified Cancers
This invention is a new bio-marker for breast and other cancers that have Her2 and Grb7 gene amplifications, thus providing a therapeutic intervention in Her2/Grb7 amplified cancers.Background40% of breast cancers, as well as several other cancer types, display increased activation of tyrosine kinases from the ErbB family, with Her2 found amplified...
Published: 8/3/2017   |   Inventor(s): Guri Tzivion, Deborah Leicht, Alexander Kaplun, Stephen Ethier
Keywords(s): Biomarker, Biotechnology, Cancer, Cancer Therapies, Therapeutics
Category(s): Diagnostic, Life Science, Oncology
Sarcoidosis and TB Biomarkers
Sarcoidosis and TB Biomarkers WSU Tech#: 15-1276 Technology Summary: This technology includes a new method for generating phage libraries and clones that are useful in discovering biomarkers from human blood samples. The inventors looked at the change in immune cells versus that of the infected tissue (BAL and blood) used this to generate bioma...
Published: 5/19/2017   |   Inventor(s): Lobelia Samavati, Harvinder Talwar, Felix Madrid, Rita Rosati, Jia Li
Keywords(s):  
Category(s): Assays, Biotechnology, Diagnostic
Easy Cell Block Device for Cytopathology and Surgical Pathology Specimens
Cell Block Device for Cytopathology and Surgical Pathology Specimens WSU Tech#: 13-1174 Technology Summary: Preparation of cell blocks is indicated from swaps or collected fluids where cells or small tissue fragments are examined. Veterinary sciences and many research labs also need good methodology to prepare high quality cell blocks wi...
Published: 5/19/2017   |   Inventor(s): Vinod Shidham, Anjani Shidham
Keywords(s):  
Category(s): Medical, Biomedical, Diagnostic, Microscopy
Vaginal microbiome snapshot (VMS)
Vaginal Microbiome Sanpshot; a Method for Diagnosing Bacterial Vaginosis and Other Vaginal Disorders WSU Tech#: 13-1141 Technology Summary: Bacterial vaginosis (BV) is a disease of the vagina caused by an imbalance of naturally occurring bacterial flora and is often confused with yeast infection (candidiasis) or infection with Trichomonas vagina...
Published: 5/19/2017   |   Inventor(s): Robert Akins, Jack Sobel
Keywords(s):  
Category(s): Assays, Biomedical, Diagnostic, Diagnostics, Infectious disease
A method to identify patients at risk for subsequent stillbirth in the third trimester
A Method to Identify and Treat Patients at Risk for Stillbirth in the 3rd TrimesterWSU Tech#: 12-1113Technology Summary: This invention is a method of identifying patients at risk for subsequent stillbirth (only due to placental related disorder) in the third trimester using a maternal blood sample. A blood sample would be obtained at the beginning...
Published: 5/19/2017   |   Inventor(s): Tinnakorn Chaiworapongsa, Roberto Romero, Sonia Hassan
Keywords(s):  
Category(s): Medical, Diagnostic, Prenatal, Small molecule, Specialty compounds, Therapeutics, Life Science
Development of a multimolecular and multimodular biomarker panel for the early screening, molecular distinction and clinical follow-up of patients developing preeclampsia/HELLP syndrome and its preparation for preclinical testing
Development of a Multimolecular and Multimodular Biomarker Panel for the Early Screening, Molecular Distinction and Clinical Follow-Up of Patients Developing Preeclampsia/HELLP Syndrome and its Preparation for Preclinical Testing WSU Tech#: 12-1110 Technology Summary: Preeclampsia is a pregnancy complication characterized by high blood pressure an...
Published: 5/19/2017   |   Inventor(s): Nandor Than, Adi Tarca, Gabor Juhasz, Adrienna Kekesi, Hamutal Meiri, Zoltan Papp, Roberto Romero
Keywords(s):  
Category(s): Medical, Biotechnology, Diagnostic, Diagnostics, Genomics/Genetics, Prenatal, Proteomics
Long non-protein-coding RNA molecules as therapeutics for epilepsy.
Long Non-Coding RNA Molecules as Therapeutics for Epilepsy WSU Tech#: 12-1089 Technology Summary: Long Non-coding RNA (lncRNA) were first described in 2002 from mouse, making this a relatively new technology. lncRNA transcripts far exceed the number of protein coding mRNAs in the mammalian transcriptome, but in lower copy numbers. Inventors ha...
Published: 5/19/2017   |   Inventor(s): Jeffrey Loeb, Leonard Lipovich
Keywords(s):  
Category(s): Medical, Bioinformatics, Biomedical, Biotechnology, Diagnostic, Diagnostics, Drug Discovery, Pharmaceuticals, Therapeutics
Method For Treating and/or Imaging Breast Cancer Using Radioactive Iodine
This invention involves treating a breast cancer patient by the administration of a radioisotope of iodine in a dosage of between 5 and 50 milliCuries over the course of a day. The therapeutic composition is designed for mammary tissue uptake and includes an inorganic radioactive iodide salt (e.g., alkali metal, alkali earth or transition met...
Published: 5/18/2010   |   Inventor(s): James Rillema
Keywords(s): Anti-cancer, Breast Cancer, Cancer Therapies, Imaging, Therapeutics
Category(s): Therapeutics, Life Science, Oncology, Receptors/targets, Diagnostic, Imaging
SIRT2 Antibody
This technology is a novel rabbit antibody for SIRT2 ( Sirtuin 2) designed to follow human SIRT2 proteins in order to determine their role in gene regulation and apoptosis.Background & Unmet Need:The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and supp...
Published: 5/11/2010   |   Inventor(s): Michael Tainsky, Sylvia Dryden
Keywords(s): Compound, Protein
Category(s): Diagnostic, Antibodies, Life Science, Research tools
Antibodies to a Novel Cell Cycle and Apoptosis Regulatory Protein (CARP) -1
Wayne State University researchers have identified a novel cDNA which encodes a pro-apoptotic protein called CARP-1 (Cell Cycle and Apoptosis Regulatory Protein-1), which is expressed in many cancer cell types including breast and colon carcinoma cells. This novel cDNA can be used as a diagnostic and prognostic tool for many types of cancer. Bac...
Published: 5/7/2010   |   Inventor(s): Arun Rishi, Joseph Fontana
Keywords(s): Antibody, Breast Cancer, Cancer, Drug Target
Category(s): Diagnostic, Life Science, Research tools, Antibodies
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