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Generation of gp78 null mice
Generation of gp78 null mice WSU Tech#: 15-1291 Technology: Generation of the first preclinical experimental model system for gp78-/- C57BL/6 mice, which spontaneously develops age-related nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC), linking endoplasmic reticulum-associated degradation (ERAD) to hepatosteatosis, cirrhosis,...
Published: 11/22/2021
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Inventor(s):
Avraham Raz
,
Andrei Golovko
Keywords(s):
Category(s):
Animal models
,
Biology
,
Biomedical
,
Biotechnology
,
Drug Delivery
,
Drug Discovery
,
Drug Screening
,
Genomics/Genetics
,
Life Science
,
Oncology
,
Research tools
Toxicological high throughput screens based on prioritized differentiation of mouse viable potency reporter, and viable first differentiated lineage reporter, mouse embryonic stem cells
Toxicological High-Throughput Screens Based on Prioritized Differentiation of Mouse Viable Potency Reporter, and Viable First Differentiated Lineage Reporter, Mouse Embryonic Stem Cells WSU Tech#: 15-1279 Technology Summary: This technology provides systems and methods to detect stress in stem cells where the detected stressor might affect all stem...
Published: 3/3/2020
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Inventor(s):
Daniel Rappolee
,
Elizabeth Puscheck
Keywords(s):
Category(s):
Drug Screening
,
Biotechnology