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Multisystemic therapy-Health Care (MST-HC)
This invention is an evidence-based behavioral treatment developed for monitoring youths with chronic health conditions and a history of poor illness management. Background & Unmet Need: The main technology for monitoring chronically ill patients with poor adherence is disease management programs. While these programs may be helpful, they are...
Published: 11/28/2017   |   Inventor(s): Deborah Ellis, Sylvie Naar-King
Keywords(s): Asthma, Diabetes, Patient Monitoring
Category(s): Life Science, Research tools, Other
Ruthenium-based caging of nitrile-containing enzyme inhibitors
Technology Summary: Novel synthesis methods for caging nitrile-containing bioactive molecules to a non-toxic ruthenium metal complex have been developed which enable light activated release of a cathespin K inhibitor. Numerous potent and selective cathepsin inhibitors are being developed as drug candidates. Cysteine cathepsins are involved in the pathophysiology...
Published: 4/29/2013   |   Inventor(s): Jeremy Kodanko, Claudia Turro
Keywords(s): Cancer, Pharmaceuticals
Category(s): Chemicals, Drug Delivery, Life Science, Physical Sciences, Other
Laser Spray Ionization (LSI) Method for Mass Spectrometry Imaging
Technology Summary: Laser Spray Ionization (LSI) is a novel inlet ionization method for mass spectrometry invented at WSU which can be used to create predominately multiply charged ions from solid samples at atmospheric pressure. Unlike MALDI ionization methods which are typically limited to producing singly charged species for larger molecules, LSI...
Published: 4/26/2013   |   Inventor(s): Sarah Trimpin, Thushani Nikeshala, Ellen Inutan, John Maarouf
Keywords(s): Biotechnology, Imaging
Category(s): Instrumentation, Imaging, Characterization, Other, Physical Sciences, Spectroscopy, Life Science, Research tools
Nano-beaker array formation process and its use for high-throughput loading and crystallization screening and other lab-on-the-chip applications
Wayne State University researchers have invented a novel process to make array patterns and its use for high-throughput screening of crystallization conditions, liquid solution applications, and other lab-on-the-chip applications. The formation process is a variation of “particle lithography” in which microparticles such as polystyrene microparticles...
Published: 11/7/2011   |   Inventor(s): Guangzhao Mao, Daniel Sobczynski, Sunxi Wang, Eugene Xhahysa, Pedram Jahanian
Keywords(s): Nanotechnology
Category(s): Physical Sciences, Microfluidics, MEMS, Life Science, Research tools, Other
Compositions, Process, and Method for Producing Hybrid Green Cements and Their Concrete Products
A Wayne State University researcher has developed a novel method to make sustainable Hybrid Green Cements (HGC) from low cost minerals and waste minerals such as coal, ash, bio-mass ash, or mine tailings. Key issues that the researcher has identified include optimal ranges of hybrid mix compositions, processing, and curing conditions. HGC provides...
Published: 11/7/2011   |   Inventor(s): Hwai-Chung Wu
Keywords(s):  
Category(s): Materials, Energy & Environment, Physical Sciences, Building & Construction, Other, Industrial & Manufacturing
GlyB4 Fusion with Neuregulin Heparin-Targeting Domain to Block Neuregulin Signaling
We have harnessed this natural targeting ability of NRG by fusing the HBD of NRG to soluble HER4. This fusion protein retains high affinity heparin binding to heparin and to cells that express heparan sulfates resulting in a more potent NRG antagonist. In vivo, it is targeted to peripheral nerve segments where it blocks the activity of NRG as a Schwann...
Published: 5/16/2011   |   Inventor(s): Jeffrey Loeb, Qunfang Lee
Keywords(s): Anti-cancer, Biotechnology, Cancer risk, Cancer Therapies, Drug Delivery, Drug Target, Epilepsy
Category(s): Life Science, Drug Delivery, Other
First Row Transition Metal Diazadiene Film Growth Precursors
Technology Overview Wayne State University researchers have developed a new class of thermally stable, volatile transition chemical compounds that have desirable properties for the growth of thin films of transition metal-containing materials. These novel film precursors have high potential for use in the growth of thin films by chemical vapor...
Published: 5/2/2011   |   Inventor(s): Charles Winter, Thomas Knisley
Keywords(s):  
Category(s): Chemicals, Materials, Other, Physical Sciences, Thin films
Vibro-acoustic metamaterial with mass and flexible stem array
WSU researchers have developed a novel device combining the effects of negative effective elastic modulus and negative effective mass, acting as local resonators that can damp out vibrations and sound at multiple frequencies. This class of metamaterials has the superior ability to attenuate sound and have a much greater ability to block dynamic disturbances....
Published: 5/2/2011   |   Inventor(s): Md Tofiqul Islam, Golam Newaz, Mohammad Hailat
Keywords(s):  
Category(s): Materials, Industrial & Manufacturing, Other, Physical Sciences, Building & Construction
Guidance and Control System for Under Actuated Marine Surface Vessels
WSU researchers have developed a guidance system that yields a faster convergence rate of the ship to its desired trajectory than existing systems. The new algorithm varies the radius in the guidance algorithm exponentially as opposed to linear variations in existing schemes. This was done to prevent the system from over-reacting for small cross track...
Published: 9/21/2010   |   Inventor(s): Nabil Chalhoub, Nassim Khaled
Keywords(s):  
Category(s): Physical Sciences, Automotive & Transportation, Other, Software
Fuel Injector to Work as an Ionization Sensor and as an Injection Signal Detector in Electronically Controlled Fuel Injection Systems in Diesel and Direct Injection Gasoline Engines
Wayne State researchers have created an invention which uses one element in the engine, the fuel injector, to perform four tasks, injecting fuel, acting as an injection pulse detector, operating as a fuel injector malfunction detector and working as an ion sensor without modifying the fuel injector. Internal combustion engine control has become more...
Published: 6/4/2010   |   Inventor(s): Fadi Estefanous
Keywords(s):  
Category(s): Electronics, Automotive & Transportation, Physical Sciences, Powertrain, Sensors, Other
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