Search Results - chemicals




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Co-polymer Stabilizers for Pressured Metered Dose Inhalers (pMDIs)
A series of novel co polymer surfactants with the general structure LAmEOnLAm were developed along with a Colloidal Probe Microscopy (CPM) method to optimize the surfactant composition using adhesion forces to improve stabilization of drug dispersions. This expands the range of biomolecules and micronized drug particles that can be formulated with ...
Published: 8/14/2013   |   Inventor(s): Sandro Da Rocha, Libo Wu
Keywords(s): Assay, Asthma, Compound, Device, Drug Delivery, Formulation, Instrumentation, Method, Pharmaceuticals, Process, Therapeutics
Category(s): Chemicals, Drug Delivery, Pharmaceuticals, Instrumentation, Materials
Ruthenium-based caging of nitrile-containing enzyme inhibitors
Technology Summary: Novel synthesis methods for caging nitrile-containing bioactive molecules to a non-toxic ruthenium metal complex have been developed which enable light activated release of a cathespin K inhibitor. Numerous potent and selective cathepsin inhibitors are being developed as drug candidates. Cysteine cathepsins are involved in the p...
Published: 4/29/2013   |   Inventor(s): Jeremy Kodanko, Claudia Turro
Keywords(s): Cancer, Pharmaceuticals
Category(s): Chemicals, Drug Delivery, Life Science, Physical Sciences, Other
Next Generation MRI Contrast Imaging Agent
WSU has developed a new class of contrast agents that are effective at ultra-high field strengths (>3 tesla) in magnetic resonance imaging (MRI) where current clinical agents severely decline in effectiveness. Our new agents are based on the metal Eu(II) which is novel compared to current agents that are based on Gd(III). The difference between ...
Published: 8/2/2012   |   Inventor(s): Matthew Allen, Nipuni Gamage, Yujiang Mei, Joel Garcia, Jeremiah Moore
Keywords(s): Compound, Diagnostic, Imaging, MRI, Positive Imaging Agent
Category(s): Imaging, Chemicals, Life Science, MRI, Physical Sciences, Specialty compounds
Solid Zn-base Catalysts for Simultaneous Transesterification and Esterification
Description: WSU researchers have developed a series of novel heterogeneous catalysts for simultaneous transesterifrication and esterifrication of fats and oils that can be used in the production of biodiesel. These catalysts are solids, a mixture of zinc oxide and other metal oxides species which provide the potential to convert all kinds of oil f...
Published: 11/23/2011   |   Inventor(s): Shuli Yan, Ka Yuen Simon Ng, Steven Salley
Keywords(s): Biodiesel
Category(s): Chemicals, Catalysts, Energy & Environment, Physical Sciences, Renewable Fuels
Graphene based support matrix to anchor bifunctional catalyst for Lithium-Air batteries
WSU researchers have developed a novel process to produce highly stable, conductive, and high surface area graphene based matrix for bifunctional catalysts for air cathodes. Given the promising stability and enhanced conductivity of the graphene matrix, the WSU researchers propose to incorporate bifunctional catalysts into a graphene matrix. Curren...
Published: 11/22/2011   |   Inventor(s): Kapila Wadumesthrige, Ka Yuen Simon Ng, Steven Salley
Keywords(s):  
Category(s): Chemicals, Materials, Energy Storage/Battery, Energy & Environment, Nanomaterials, Physical Sciences, Catalysts, Automotive & Transportation, Battery
Dispersion-optimized Silicon nanoparticle (SiNP)/Graphene composite anode for high performance Lithium ion battery (LIB)
WSU researchers have invented a novel method to produce dispersion-optimized SiNP within a conducting Graphene matrix forming a standalone composite anode material. The method creates small clusters to lone particle distributions maximizing the nanomaterial properties of SiNP yielding anodes with improved capacity retention and rate performance. It...
Published: 11/7/2011   |   Inventor(s): Rhet C De Guzman, Ka Yuen Simon Ng, Steven Salley
Keywords(s):  
Category(s): Chemicals, Materials, Energy & Environment, Energy Storage/Battery, Nanomaterials, Physical Sciences
First Row Transition Metal Diazadiene Film Growth Precursors
Technology Overview Wayne State University researchers have developed a new class of thermally stable, volatile transition chemical compounds that have desirable properties for the growth of thin films of transition metal-containing materials. These novel film precursors have high potential for use in the growth of thin films by chemical vap...
Published: 5/2/2011   |   Inventor(s): Charles Winter, Thomas Knisley
Keywords(s):  
Category(s): Chemicals, Materials, Other, Physical Sciences, Thin films
Combined Homogeneous and Heterogeneous Catalytic Transesterification Process for Biodiesel Production
WSU researchers developed a combined heterogeneous and homogeneous catalyst that reduces overall production costs, expands feedstock options, and enables large volume production in a continuous process as compared to traditional homogeneous biodiesel catalysts. This unique catalytic transesterification process works better with ethanol compared to...
Published: 8/17/2010   |   Inventor(s): Manhoe Kim, Steven Salley, Ka Yuen Simon Ng
Keywords(s):  
Category(s): Catalysts, Chemicals, Physical Sciences, Renewable Fuels, Energy & Environment
Biologically active ATP-Analogs for tagging phosphoproteins
A novel Photo Cross Linking Assay (PCLA) for targeting protein phosphorylation Protein phosphorylation catalyzed by kinases and phosphatases act at critical control points that regulates many cellular processes. This central role makes them an attractive target for identifying largely untapped and important biomarkers for disease diagnostics. Under...
Published: 5/11/2010   |   Inventor(s): Mary Pflum
Keywords(s): Assay, Biomarker, Protein
Category(s): Chemicals, Life Science, Research tools, Assays, Reagents
Development of TiO2 Anatase Thin Films Grown by Pulsed DC Magnetron Reactive Sputtering for Device Applications
WSU researchers have developed a novel procedure for creating Titanium Dioxide (TiO2) thin films using anatase material. Procedure uses TiO2 thin film with single phase a textured material and reproducible with different thickness on amorphous and crystalline substrates. Anatase is attracting much interest for its unique properties and has valuable...
Published: 5/11/2010   |   Inventor(s): Ibrahim AL-Houmoudi, Golam Newaz, Gregory Auner, Ratna Naik
Keywords(s): Anti Reflection, Sensors
Category(s): Chemicals, Materials, Thin films, Physical Sciences, Sensors, Industrial & Manufacturing, Other
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