Search Results - diagnostics




3 Results Sort By:
Translation Regulated (TR)-Mediated Gene Expression: Novel Expression and Reporter Vectors
Background: Often referred to as the crucial "drug discovery tool", cell based technology is one of the most significant sectors of pharmaceutical research and development. Of particular importance has been the development of information-rich cellular assays that determine drug candidate efficacy and safety (target identification, valida...
Published: 8/14/2013   |   Inventor(s): Leon Carlock, Maria Cypher
Keywords(s): Animal Model, Anti-cancer, Cancer, Cancer risk, Cancer Therapies, Diagnostics, Imaging, Therapeutics
Category(s): Life Science, Diagnostics, Research tools, Assays, Cell lines
A Diagnostic Marker for Matrix Metalloprotease (MMP)-2 and -9 Activity in Cancer Tissue
This invention is a new and simple method for the identification of active versus latent matrix metalloprotease enzymes (MMPs) in tissue. Background & Unmet Need: MMPs are involved in tumor progression and therefore are targets for anti-cancer drug therapies. However, most drug therapies directed at inhibition of MMPs have failed because there...
Published: 5/6/2010   |   Inventor(s): Avraham Raz, Rafael Fridman, Pratima Nangia-maker
Keywords(s): Biomarker, Cancer, Diagnostics, Enzyme, Method
Category(s): Life Science, Oncology, Research tools, Antibodies, Therapeutics, Diseases
Imaging Tandem Mass Spectrometry: Reduction to Practice
Currently, tandem mass spectrometry is typically performed by selecting a single mass peak in a time of flight or quadrupole mass spectrometer, which is then fragmented through collision, after which the products are mass-selected in a quadrupole or similar secondary mass spectrometer. A Wayne State University researcher has developed an alter...
Published: 5/6/2010   |   Inventor(s): Arthur Suits, Myung Kim, Brian Leskiw
Keywords(s): Diagnostics, Instrumentation, Method
Category(s): Instrumentation, Physical Sciences, Spectroscopy, Imaging, Other