Search Results - infectious disease

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Activated T Cells and Activated T Cells Armed with BiSpecific Antibodies Directed at Cancer Antigens are Poor Responders to Alloantigens May Help Engraftment and Improve Anti-Tumor Effects

BackgroundThe treatment of hematologic malignancies with allogeneic stem cell transplant is limited by the numbers of allogeneic donors. Umbilical cord blood stem transplants have been an important alternative source of hematopoietic stem cells. However, failure or delayed engraftment remains the critical barrier to the success of the transplants...

Published: 8/3/2017 | Inventor(s): Lawrence Lum

Keywords(s): Anti-cancer

Category(s): Life Science, Therapeutics, Diseases, Infectious disease

Use of Raman Spectroscopy to Decrease Time to Identify the Species of Candida and bacterial Growth in Cultures.

Use of Raman Spectroscopy to Decrease Time to Identify MRSA Verses MSSA and the Subspecies of Candida and bacterial Growth in Cultures WSU Tech#: 15-1270 Technology Summary: New Technology for the identification of MRSA versus MSSA and sub-species for both bacterial staph Aureus (SA) and Candida in one package, using Raman Spectroscopy. This wo...

Published: 5/19/2017 | Inventor(s): Nitin Chouthai

Keywords(s):

Category(s): Imaging, Drug Discovery, Infectious disease, Instrumentation, Software

Vaginal microbiome snapshot (VMS)

Vaginal Microbiome Sanpshot; a Method for Diagnosing Bacterial Vaginosis and Other Vaginal Disorders WSU Tech#: 13-1141 Technology Summary: Bacterial vaginosis (BV) is a disease of the vagina caused by an imbalance of naturally occurring bacterial flora and is often confused with yeast infection (candidiasis) or infection with Trichomonas vagina...

Published: 5/19/2017 | Inventor(s): Robert Akins, Jack Sobel

Keywords(s):

Category(s): Assays, Biomedical, Diagnostic, Diagnostics, Infectious disease

Antibacterial activity of natural compounds and their synthetic analogue: A potential new antibiotic with potent activity against multiple drug resistant bacterial pathogens

Our researchers have developed novel compounds that are potential antibiotics useful for treatment against the deadly bacteria MRSA (methicillin-resistant Staphylococcus aureus), VRE (vancomycin-resistant Enterococcus faecium), and several other well-known common infectious agents.Background & Unmet Need:Before antibiotics became available in t...

Published: 5/12/2015 | Inventor(s): Fazlul Sarkar, Hossein Salimnia, Subhash Padhye, Bernhard Biersack

Keywords(s): Analog or Analogue, Antibiotics, Anti-infective, Anti-microbial, Disease

Category(s): Biologicals, Diseases, Infectious disease, Life Science, Therapeutics

Using Flagellin to Prevent and to Treat Inflammation Associated Gram Negative Bacterial Infection

This technology provides a new method for treating inflammatory diseases by using a Gram negative bacterial component that results in increased tolerance and immunity. Background & Unmet Need: Despite advances of modern medicine, bacterial sepsis remains one of the major threats to human health worldwide. In the US alone, it affects approxima...

Published: 5/18/2010 | Inventor(s): Fu-shin Yu, Ashok Kumar, Jing Zhang, Linda Hazlett

Keywords(s): Anti-microbial, Asthma

Category(s): Therapeutics, Diseases, Life Science, Infectious disease

Mannich Bases of Conjugated Styryl Ketones

Detailed Description Human infectious diseases caused by fungi have increased markedly during the past 10 years due mainly to advances in medical care that involve prolonged immune suppression increased use of cytotoxic drugs in cancer chemotherapy and the advent of AIDS. As a result organisms such as Candida albicans have become opportunistic...

Published: 5/18/2010 | Inventor(s): Jonathan Dimmock, Elias Manavathu

Keywords(s): Anti-infective, Therapeutics

Category(s): Therapeutics, Life Science, Infectious disease

Designer Aminoglycosides

Wayne State University researchers have synthesized a series of novel aminoglycoside antibiotics that have shown enhanced antibacterial activity, low susceptibility to existing resistance mechanisms and low toxicity when compared to currently marketed aminoglycosides. Aminoglycoside antibiotics have been used against a wide variety of bacteria...

Published: 5/6/2010 | Inventor(s): Shahriar Mobashery, Lakshmi Kotra, Jalal Haddad

Keywords(s): Antibiotics

Category(s): Therapeutics, Life Science, Small molecule, Diseases, Infectious disease