Search Results - instrumentation

7 Results

Sort By:

Microfluidic platforms for live-cell imaging and bio/pathomimetic tissue models

Background:Methodologies to image and quantify tissue models using high-content analysis (HCI) and functional analyses of 3D avatars are needed as such avatars better recapitulate the phenotype of pathobiological processes and better predict efficacy of, and resistance to, a wide variety of therapies. Furthermore, changes in morphometry, viability,...

Published: 2/14/2022 | Inventor(s): Bonnie Sloane, Kamiar Moin, Kyungmin Ji, Kingsley Osuala, Yong Xu, Hongen Tu

Keywords(s):

Category(s): Specialty compounds, Research tools, Oncology, Microfluidics, Life Science, Instrumentation, Imaging, Diseases, Devices, Cell lines

Use of Raman Spectroscopy to Decrease Time to Identify the Species of Candida and bacterial Growth in Cultures.

Use of Raman Spectroscopy to Decrease Time to Identify MRSA Verses MSSA and the Subspecies of Candida and bacterial Growth in Cultures WSU Tech#: 15-1270 Technology Summary: New Technology for the identification of MRSA versus MSSA and sub-species for both bacterial staph Aureus (SA) and Candida in one package, using Raman Spectroscopy. This work...

Published: 2/9/2022 | Inventor(s): Nitin Chouthai

Keywords(s):

Category(s): Imaging, Drug Discovery, Infectious disease, Instrumentation, Software

Co-polymer Stabilizers for Pressured Metered Dose Inhalers (pMDIs)

A series of novel co polymer surfactants with the general structure LAmEOnLAm were developed along with a Colloidal Probe Microscopy (CPM) method to optimize the surfactant composition using adhesion forces to improve stabilization of drug dispersions. This expands the range of biomolecules and micronized drug particles that can be formulated with pMDIs....

Published: 11/11/2021 | Inventor(s): Sandro Da Rocha, Libo Wu

Keywords(s): Assay, Asthma, Compound, Device, Drug Delivery, Formulation, Instrumentation, Method, Pharmaceuticals, Process, Therapeutics

Category(s): Chemicals, Drug Delivery, Pharmaceuticals, Instrumentation, Materials

Laser Spray Ionization (LSI) Method for Mass Spectrometry Imaging

Technology Summary: Laser Spray Ionization (LSI) is a novel inlet ionization method for mass spectrometry invented at WSU which can be used to create predominately multiply charged ions from solid samples at atmospheric pressure. Unlike MALDI ionization methods which are typically limited to producing singly charged species for larger molecules, LSI...

Published: 5/1/2018 | Inventor(s): Sarah Trimpin, Thushani Nikeshala, Ellen Inutan, John Maarouf

Keywords(s): Biotechnology, Imaging

Category(s): Instrumentation, Imaging, Characterization, Other, Physical Sciences, Spectroscopy, Life Science, Research tools

Marangoni Optofluidic Tweezers (MOT)

There is currently a great deal of interest in using small droplets as containers for chemical reactions. Optical methods for droplet manipulation are attractive because they offer control without an on chip structure; however forces from optical tweezers tend to be in the pN range. Wayne State University researchers have developed a new method...

Published: 5/19/2017 | Inventor(s): Amar Basu, Gopakumar Kamalakshakurup

Keywords(s):

Category(s): MEMS, Microfluidics, Physical Sciences, Instrumentation, Optics & Photonics

Sub-monolayer detection with surface selective vibrational spectroscopy

This invention describes a new system and method for performing surface-selective spectroscopic detection with high sensitivity and low detection limits particularly in the visible and fingerprint mid-infrared spectral regions. The method offers a substantial improvement, 10-fold or more, over existing techniques. This invention has already been reduced...

Published: 11/11/2021 | Inventor(s): Alexander Benderskii, Igor Stiopkin, Himali Jayathilake

Keywords(s): Device, Instrumentation, Method, Nanotechnology, Optical, Photonic

Category(s): Instrumentation, Spectroscopy, Physical Sciences

Imaging Tandem Mass Spectrometry: Reduction to Practice

Currently, tandem mass spectrometry is typically performed by selecting a single mass peak in a time of flight or quadrupole mass spectrometer, which is then fragmented through collision, after which the products are mass-selected in a quadrupole or similar secondary mass spectrometer. A Wayne State University researcher has developed an alternative...

Published: 5/19/2017 | Inventor(s): Arthur Suits, Myung Kim, Brian Leskiw

Keywords(s): Diagnostics, Instrumentation, Method

Category(s): Instrumentation, Physical Sciences, Spectroscopy, Imaging, Other