Search Results - joseph+fontana

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Anti-Cancer Activity of a 2,5-Substituted Pyrimidine

This technology is a novel class of compounds that induce apoptosis in cancerous cells. BackgroundARR molecules (adamantyl-substituted retinoid-related) are a unique class of compounds which have been found to induce apoptosis, or cell death, in a large number of tumor types. SHP plays a role in cellular proliferation. Molecules that Interfere with...

Published: 12/7/2022 | Inventor(s): Joseph Fontana, Ramzi Mohammad, Lulu Farhana, Amro Aboukameel, Marcia Dawson, Zebin Xia

Keywords(s): Analog or Analogue, Anti-cancer

Category(s): Life Science, Oncology, Therapeutics, Diseases

Antibodies to a Novel Cell Cycle and Apoptosis Regulatory Protein (CARP) -1

Wayne State University researchers have identified a novel cDNA which encodes a pro-apoptotic protein called CARP-1 (Cell Cycle and Apoptosis Regulatory Protein-1), which is expressed in many cancer cell types including breast and colon carcinoma cells. This novel cDNA can be used as a diagnostic and prognostic tool for many types of cancer. Background...

Published: 2/8/2022 | Inventor(s): Arun Rishi, Joseph Fontana

Keywords(s): Antibody, Breast Cancer, Cancer, Drug Target

Category(s): Diagnostic, Life Science, Research tools, Antibodies