Search Results - protein%2fpeptides

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Disulfide by Design 2.0: A web-based tool for disulfide engineering in proteins

Background:Immunoinformatics employs a computer-driven approach to identifying fragments of the target pathogen that would provide a suitable vaccine, avoiding potential safety concerns from the more traditional approach of using whole pathogens. Immunoinformatics now plays a crucial role in vaccine design, immunodiagnostic development, and antibody...

Published: 4/18/2022 | Inventor(s): Alan Dombkowski, Douglas Craig

Keywords(s): Coronavirus, COVID-19

Category(s): Life Science, Software, Simulation & Modeling, Research tools, Computer Software, Protein/peptides

A Gene Knockout Mouse Model to Study Lung Disease and a Lung Disease Drug Target

Our researchers have created a gene knockout mouse model that lacks the cytochrome c oxidase subunit IV-2 in order to study the gene’s effects on controlling asthma. Background & Unmeet Need: Asthma is an inflammatory disease of the airways that affects 155 million people of all ages worldwide. Cytochome c oxidase (CcO) is a multi-subunit...

Published: 12/17/2024 | Inventor(s): Maik Huettemann, Lawrence Grossman, David Bassett

Keywords(s): Asthma, Disease, Drug Target, Gene, Knock-out, Lung, Mouse Model

Category(s): Animal models, Biological materials, Life Science, Research tools, Protein/peptides