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Para-Amino Substituent on the D Ring of Green Tea Polyphenol Epigallocatechin-3-Gallate as Novel Proteasome Inhibitor and Cancer Apoptosis Inducer

This technology is a group of (-)EGCG analogs with stable and improved anti-tumor activities. Background & Unmet Need:Catechins are a type of plant-derived antioxidant whose biological activities may play an effect on cancer prevention. Green tea has long been lauded to have ingredients that protect cells from the DNA damage that causes cancer. The...

Published: 8/3/2017 | Inventor(s): Qingping Dou, Kristin Landis-Piwowar, Tak-Hang Chan, Kumi Osanai

Keywords(s): Anti-cancer, Breast Cancer, Compound, Prostate Cancer

Category(s): Life Science, Oncology, Therapeutics, Diseases