Search Results - xiang-shu+fei




1 Results Sort By:
Novel Hybrid Series of Compound Derived from 2-Aminotetralin and Piperazine Based Derivatives: Characterization for D1, D2, D3, D4 and other Serotonin Receptor Subtypes Binding
A series of compounds derived from 2-aminotetralin and piperazine fragments have been synthesized, which exhibit high CNS activity in vivo and in vitro. Some of the selected lead compounds have exhibited potent in vivo activity in a Parkinson’s disease animal model with long extended duration of action. In particular, these compounds show high...
Published: 5/6/2010   |   Inventor(s): Aloke Dutta, Xiang-Shu Fei
Keywords(s):  
Category(s): Therapeutics, Diseases, Life Science, Small molecule, Neurological disorders