Regulators of Peritoneal Healing and Adhesion Development

Case ID:
03-629

WSU researchers have identified a novel approach to reduce postoperative adhesion development.  This invention identifies new targets for regulation of healing and fibrosis, so as to decrease or increase the process depending on the clinical need.  NF-kappa has shown to be differently expressed in fibroblasts from normal peritoneum and adhesions.  We propose that modification of the expression of this molecule will allow for regulation of peritoneal healing, and tissue fibrosis including modulation of acute and chronic pathologic processes. 

Commercial Application

  • Reduction of postoperative adhesion development

Technological Advantage

  • New targets for the regulation of healing and fibrosis

Patent Status

Patentability is being assessed

Patent Information:
Category(s):
Biotechnology
For Information, Contact:
Joan Dunbar
Associate Vice President for Technology Commercialization
Wayne State University
(313) 577-5542
jcdunbar@med.wayne.edu
Inventors:
Michael Diamond
Ghassan Saed
Keywords: