WSU researchers have identified a novel approach to reduce postoperative adhesion development. This invention identifies new targets for regulation of healing and fibrosis, so as to decrease or increase the process depending on the clinical need. NF-kappa has shown to be differently expressed in fibroblasts from normal peritoneum and adhesions. We propose that modification of the expression of this molecule will allow for regulation of peritoneal healing, and tissue fibrosis including modulation of acute and chronic pathologic processes.
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Patentability is being assessed