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Generation of gp78 null mice
Generation of gp78 null mice
WSU Tech#: 15-1291
Technology:
Generation of the first preclinical experimental model system for gp78-/- C57BL/6 mice, which spontaneously develops age-related nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC), linking endoplasmic reticulum-associated degradation (ERAD) to hepatosteatosis, cirrhosis,...
Published: 9/15/2025
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Inventor(s): Avraham Raz, Andrei Golovko
Keywords(s):
Category(s): Technology Category > Research tools, Technology Category > Oncology, Technology Category > Life Science, Technology Category > Genomics/Genetics, Technology Category > Drug Screening, Technology Category > Drug Delivery, Technology Category > Drug Discovery, Technology Category > Biomedical, Technology Category > Biotechnology, Technology Category > Biology, Technology Category > Animal models
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Sarcoidosis and TB Biomarkers
Sarcoidosis and TB Biomarkers
WSU Tech#: 15-1276
Technology Summary:
This technology includes a new method for generating phage libraries and clones that are useful in discovering biomarkers from human blood samples. The inventors looked at the change in immune cells versus that of the infected tissue (BAL and blood) used this to generate biomarkers...
Published: 9/15/2025
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Inventor(s): Lobelia Samavati, Harvinder Talwar, Felix Madrid, Rita Rosati, Jia Li
Keywords(s):
Category(s): Technology Category > Diagnostic, Technology Category > Biotechnology, Technology Category > Assays
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GENERATION OF 5-FLUOROURACIL + OXALIPLATIN RESISTANT COLON CANCER CELLS: A TOOL TO STUDY CANCER RECURRENCE AND DRUG RESISTANCE
Generation of 5-Fluorouracil + Oxaliplatin Resistant Colon Cancer Cells
WSU Tech#: 13-1154
Technology Summary:
A significant obstacle for the successful management of patients with colorectal cancer (CRC) is intrinsic drug resistance or, in patients who respond to chemotherapy, acquired drug resistance. Drug resistance can occur through a variety...
Published: 9/15/2025
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Inventor(s): Adhip Majumdar, Yingjie Yu
Keywords(s):
Category(s): Technology Category > Research tools, Technology Category > Oncology, Technology Category > Drug Discovery, Technology Category > Characterization, Technology Category > Cell lines, Technology Category > Biotechnology, Technology Category > Biomedical
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Long non-protein-coding RNA molecules as therapeutics for epilepsy.
Long Non-Coding RNA Molecules as Therapeutics for Epilepsy
WSU Tech#: 12-1089
Technology Summary:
Long Non-coding RNA (lncRNA) were first described in 2002 from mouse, making this a relatively new technology. lncRNA transcripts far exceed the number of protein coding mRNAs in the mammalian transcriptome, but in lower copy numbers. Inventors...
Published: 9/15/2025
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Inventor(s): Jeffrey Loeb, Leonard Lipovich
Keywords(s):
Category(s): Technology Category > Therapeutics, Technology Category > Pharmaceuticals, Technology Category > Medical, Technology Category > Life Science, Technology Category > Drug Discovery, Technology Category > Diagnostic, Technology Category > Diagnostics, Technology Category > Biotechnology, Technology Category > Biomedical, Technology Category > Bioinformatics
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Sentinel Cell
Sentry Cell (Macrophage Hazardous Material Detection)
WSU Tech#: 10-991
Technology
Summary:
This technology is designed around an isolated cell
system for the detection of an energetic material comprising of an isolated
stationary macrophage cell isolated from a vestibular labyrinth of a Opsanus
sp. This macrophage cell is plated
in...
Published: 9/15/2025
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Inventor(s): Robert Silver
Keywords(s): Imaging, Process, Research Tool
Category(s): Technology Category > Safety, Technology Category > Process/Procedure, Technology Category > Environment, Technology Category > Biotechnology
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