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Isoform-selective HDAC inhibitors
Selective C4-modified SAHA analogs inhibit HDAC6 and HDAC8 enzymes for targeted therapeutic applications.
Technology Summary
Histone deacetylase (HDAC) proteins are key players in cancer progression and have emerged recently as targets for anti-cancer drugs. WSU researchers have synthesized a variety of small molecule HDAC...
Published: 6/16/2026
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Inventor(s): Mary Pflum
Keywords(s):
Category(s): Technology Category > Biomedical, Technology Category > Chemical Processing/Synthesis, Technology Category > Characterization, Technology Category > Life Science, Technology Category > Oncology, Technology Category > Pharmaceuticals, Technology Category > Research tools, Technology Category > Small molecule
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Insulin Crystals Removal Platform
Description:
A platform technology for improving insulin delivery by removing insulin-derived fibrils through polyester membrane filtration.
This invention employs membrane filters integrated into insulin delivery systems to selectively remove insulin-derived fibrils (IDFs) from insulin formulations. By filtering out fibrils while preserving active...
Published: 1/27/2026
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Inventor(s): Ulrike Klueh
Keywords(s):
Category(s): Technology Category > Biomedical, Technology Category > Devices, Technology Category > Drug Delivery, Technology Category > Life Science, Technology Category > Medical Devices
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Human Tissue-Engineered Inflammatory Model of Atherosclerosis
A novel, biologically engineered human blood vessel model that accurately replicates atherosclerosis for advanced preclinical research.
Technology Summary
This technology creates the first authentic human tissue-level in vitro model of atherosclerosis using a proprietary ring stacking method to build three-layered blood vessels entirely from human...
Published: 1/9/2026
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Inventor(s): Mai Lam
Keywords(s):
Category(s): Technology Category > Biomedical, Technology Category > Research tools, Technology Category > Simulation & Modeling, Technology Category > Driving Lifelong Health, Technology Category > Cardiology, Technology Category > Biomaterials, Technology Category > Life Science
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