Search Results - mary+pflum




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Isoform-selective HDAC inhibitors
Selective C4-modified SAHA analogs inhibit HDAC6 and HDAC8 enzymes for targeted therapeutic applications. Technology Summary Histone deacetylase (HDAC) proteins are key players in cancer progression and have emerged recently as targets for anti-cancer drugs. WSU researchers have synthesized a variety of small molecule HDAC...
Published: 6/16/2026   |   Inventor(s): Mary Pflum
Keywords(s):  
Category(s): Technology Category > Biomedical, Technology Category > Chemical Processing/Synthesis, Technology Category > Characterization, Technology Category > Life Science, Technology Category > Oncology, Technology Category > Pharmaceuticals, Technology Category > Research tools, Technology Category > Small molecule
Cell permeable ATP analogs
A novel ATP analog featuring a polyamine linker enables efficient kinase-catalyzed biotinylation within live cells by enhancing cell permeability. Technology Summary ATP (adenosine 5’-triphosphate) analogs such as ATP-biotin are widely used to monitor biochemical events in vitro. WSU researchers developed a specially...
Published: 6/16/2026   |   Inventor(s): Mary Pflum
Keywords(s):  
Category(s): Technology Category > Assays, Technology Category > Biology, Technology Category > Life Science, Technology Category > Research tools, Technology Category > Chemical Processing/Synthesis