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Discovery of Well Defined Sulfated Glycopolymers as Specific Heparanase Inhibitors for Cancer Therapeutics
The remodeling of the extracellular matrix has been shown to be highly upregulated in cancer and inflammation and is critically linked to the processes of invasion and metastasis. The finding that heparanase is elevated in a wide variety of tumor types and is subsequently linked to the development of pathological processes has led to an explosion of...
Published: 9/15/2025
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Inventor(s): Hien Nguyen, Ravi Loka, Eric Sletten, Israel Vlodavsky
Keywords(s): Cancer, Cancer Therapies, Pharmaceuticals, Therapeutics
Category(s): Technology Category > Therapeutics, Technology Category > Pharmaceuticals, Technology Category > Oncology, Technology Category > Life Science
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