Search Results - breast+cancer

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Using Nanotechnology to Target Aggressive Cancers

A modified gold nanoparticle is used to target aggressive triple negative breast cancer and melanoma by inhibiting RAD6 which is overexpressed in aggressive and chemoresistant cancers. Technology Summary This technology utilizes gold nanoparticles (GNPs) conjugated with a small molecule inhibitor (SMI#9) designed to target RAD6, a protein overexpressed...

Published: 8/22/2025 | Inventor(s): Malathy Shekhar, Guangzhao Mao, Yanhua Zhang

Keywords(s): Breast Cancer, Nanotechnology

Category(s): Life Science, Oncology, Drug Delivery, Therapeutics, Cancer, Nanomaterials

EL4-E2 Cell Line

This technology is a targeted anti-HER2 cell line that can be used as a research tool to develop HER2‑based vaccines for the treatment of aggressive breast cancer. Background & Unmet Need: The human epidermal growth factor 2 (HER2) is overexpressed in approximately 20-30% of all breast cancers and is associated with more aggressive and proliferative...

Published: 3/24/2022 | Inventor(s): Wei-Zen Wei

Keywords(s): Breast Cancer

Category(s): Cell lines, Life Science, Research tools, Biological materials

Transgenic Mice Carrying Wild Type Human Her-2 Under the Whey Acidic Promoter

This technology is an animal model designed to help pharmaceutical and biotechnology industries develop Her-2 based vaccines or immunotherapeutic agents. Background & Unmet Need: Her-2 positive breast cancer is a breast cancer that is positive for a protein called human epidermal growth factor receptor 2 (Her-2). Presence of Her-2 promotes...

Published: 5/13/2025 | Inventor(s): Wei-Zen Wei, Ye-Shih Ho, Marie Piechocki

Keywords(s): Animal Model, Breast Cancer, Research Tool

Category(s): Animal models, Life Science, Research tools