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Methods For The Prediction Of Drug Penetration and Exposure In The Human Brain
Description:
A novel 9‑compartment physiologically based pharmacokinetic model was developed and fully validated for prediction of heterogeneous drug distribution and exposure in the human central nervous system (CNS) and brain tumors. The 9-compartment model accounts for the general anatomical structure and pathophysiology of the human CNS and brain...
Published: 11/21/2025
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Inventor(s): Jing Li, Seongho Kim, Charuka Wickramasinghe
Keywords(s):
Category(s): Technology Category > Life Science, Technology Category > Method, Technology Category > Drug Screening, Technology Category > Drug Delivery
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