|
Transgenic Mouse Model for Marfan Syndrome Research
Description:
A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025
|
Inventor(s): Li Li, Shichao Wu, Jiawei Zhao
Keywords(s):
Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic
|
|
Portable Thermal Nitric Oxide Generation Technology
Novel chemical composition that enables pure NO gas release upon heat.
Technology Summary
This technology enables safe, efficient, and portable generation of medical-grade nitric oxide (NO) by thermally activating a bench-stable solid-state NO-releasing molecule embedded in a porous polymer matrix. FDA approved Inhaled nitric...
Published: 12/16/2025
|
Inventor(s): James Bour, Shuxiao Li
Keywords(s):
Category(s): Technology Category, Technology Category > Medical Devices, Technology Category > Drug Delivery, Technology Category > Driving Lifelong Health, Technology Category > Life Science
|
|
Low-Cost High-Performance 3D LiDAR Imaging System
Description:
This innovative 3D imaging system uses time-of-flight measurement of photons with a conventional global shutter CMOS camera to generate accurate distance data converted into brightness levels. It includes a laser source, camera, delay generator, master trigger, and electronic control unit (ECU) which together capture and average multiple...
Published: 12/16/2025
|
Inventor(s): Wen Li, Suk Kyoung Lee, Blessed Oguh, Sulaiman Abubakar
Keywords(s):
Category(s): Technology Category > Automotive & Transportation, Technology Category > Physical Sciences, Technology Category > Image Analysis (Cameras & Software), Technology Category > Revolutionizing Mobility
|
|
Methods For The Prediction Of Drug Penetration and Exposure In The Human Brain
Description:
A novel 9‑compartment physiologically based pharmacokinetic model was developed and fully validated for prediction of heterogeneous drug distribution and exposure in the human central nervous system (CNS) and brain tumors. The 9-compartment model accounts for the general anatomical structure and pathophysiology of the human CNS and brain...
Published: 11/21/2025
|
Inventor(s): Jing Li, Seongho Kim, Charuka Wickramasinghe
Keywords(s):
Category(s): Technology Category > Life Science, Technology Category > Method, Technology Category > Drug Screening, Technology Category > Drug Delivery
|
