Search Results - protein

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Tx2 metal-binding tag for purification and identification of recombinant proteins

Tx2 Metal-Binding Tag for Purification and Identification of Recombinant Proteins WSU Tech#: 11-1058Technology Summary: The technology is a new method of protein purification similar to the principles behind that of a histidine and Ni column system. The new technology uses a different amino acid sequence for generating a metal-binding cluster:T: “H...

Published: 2/28/2022 | Inventor(s): Jian-Ping Jin

Keywords(s): Assay, Biotechnology, Process, Protein, Reagents, Tool

Category(s): Life Science, Research tools, Protein/peptides

Modified Ectodomain of Human EGFR as a Potential Anticancer Agent

Development of a protein that attenuates EGFR and/or EGFR family members and is comprised of a modified EGFR ectodomain. The protein inhibits signaling via the EGFR and/or EGFR family members. The protein includes a portion of the EGFR (or EGFR family member) and the "U" region epitope of EGFR related protein (ERRP), wherein the portion of...

Published: 8/16/2021 | Inventor(s): Adhip Majumdar, Arun Rishi, Yingjie Yu

Keywords(s): Breast Cancer, Cancer, Cancer Therapies, Disease, Drug Target, Protein, Therapeutics

Category(s): Life Science, Biologicals, Diseases, Oncology

High Efficient Reagent that Transfers Protein into the Living Mammalian Cells

This invention is a new protein transduction method for efficient delivery of exogenous proteins into mammalian cells. In contrast to known protein transduction methods, this new approach has the capability of targeting transduced proteins to different cellular compartments, as well as protecting the proteins from degradation by cellular proteases....

Published: 11/9/2021 | Inventor(s): Qianqian Li, Jianjun Wang

Keywords(s): Protein

Category(s): Biotechnology, Life Science, Reagents, Research tools

Hox B4

This invention is a novel therapy for cancer using Hox B4 to induce apoptosis in leukemia cell lines. Background & Unmet Need: B‑cell chronic lymphocytic leukemia is the most common type of leukemia in adults. The B cells grow uncontrollably and invade the bone marrow and blood where they crowd out the healthy cells. There is a need to...

Published: 10/5/2018 | Inventor(s): Kamal Mubarak, Ramzi Mohammad, Robert Pauley, Larry Tait

Keywords(s): Anti-cancer, Gene, Protein

Category(s): Therapeutics, Life Science, Oncology, Diseases

New Technology of Production of Properly Folded Protein

Published: 3/2/2022 | Inventor(s): Jianjun Wang, Qianqian Li

Keywords(s): Protein

Category(s): Biotechnology, Life Science, Reagents, Research tools

SIRT2 Antibody

This technology is a novel rabbit antibody for SIRT2 ( Sirtuin 2) designed to follow human SIRT2 proteins in order to determine their role in gene regulation and apoptosis.Background & Unmet Need:The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress...

Published: 2/18/2022 | Inventor(s): Michael Tainsky, Sylvia Dryden

Keywords(s): Compound, Protein

Category(s): Diagnostic, Antibodies, Life Science, Research tools

New Technology of Studying Protein Structure/Folding Functions in Living Mammalian Cells

Published: 11/9/2021 | Inventor(s): Qianqian Li, Jianjun Wang

Keywords(s): Protein

Category(s): Life Science, Reagents, Research tools