Search Results - protein




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Modified Ectodomain of Human EGFR as a Potential Anticancer Agent
Development of a protein that attenuates EGFR and/or EGFR family members and is comprised of a modified EGFR ectodomain. The protein inhibits signaling via the EGFR and/or EGFR family members. The protein includes a portion of the EGFR (or EGFR family member) and the "U" region epitope of EGFR related protein (ERRP), wherein the portion o...
Published: 8/3/2017   |   Inventor(s): Adhip Majumdar, Arun Rishi, Yingjie Yu
Keywords(s): Breast Cancer, Cancer, Cancer Therapies, Disease, Drug Target, Protein, Therapeutics
Category(s): Life Science, Biologicals, Diseases, Oncology
High Efficient Reagent that Transfers Protein into the Living Mammalian Cells
This invention is a new protein transduction method for efficient delivery of exogenous proteins into mammalian cells. In contrast to known protein transduction methods, this new approach has the capability of targeting transduced proteins to different cellular compartments, as well as protecting the proteins from degradation by cellular prote...
Published: 6/22/2010   |   Inventor(s): Qianqian Li, Jianjun Wang
Keywords(s): Protein
Category(s): Biotechnology, Life Science, Reagents, Research tools
Hox B4
This invention is a novel therapy for cancer using Hox B4 to induce apoptosis in leukemia cell lines. Background & Unmet Need: B‑cell chronic lymphocytic leukemia is the most common type of leukemia in adults. The B cells grow uncontrollably and invade the bone marrow and blood where they crowd out the healthy cells. There is a need to...
Published: 5/18/2010   |   Inventor(s): Kamal Mubarak, Ramzi Mohammad, Robert Pauley, Larry Tait
Keywords(s): Anti-cancer, Gene, Protein
Category(s): Therapeutics, Life Science, Oncology, Diseases
New Technology of Production of Properly Folded Protein
This invention is a new protein transduction method for efficient delivery of exogenous proteins into mammalian cells. In contrast to known protein transduction methods, this new approach has the capability of targeting transduced proteins to different cellular compartments, as well as protecting the proteins from degradation by cellular prote...
Published: 5/13/2010   |   Inventor(s): Jianjun Wang, Qianqian Li
Keywords(s): Protein
Category(s): Biotechnology, Life Science, Reagents, Research tools
Biologically active ATP-Analogs for tagging phosphoproteins
A novel Photo Cross Linking Assay (PCLA) for targeting protein phosphorylation Protein phosphorylation catalyzed by kinases and phosphatases act at critical control points that regulates many cellular processes. This central role makes them an attractive target for identifying largely untapped and important biomarkers for disease diagnostics. Under...
Published: 5/11/2010   |   Inventor(s): Mary Pflum
Keywords(s): Assay, Biomarker, Protein
Category(s): Chemicals, Life Science, Research tools, Assays, Reagents
SIRT2 Antibody
This technology is a novel rabbit antibody for SIRT2 ( Sirtuin 2) designed to follow human SIRT2 proteins in order to determine their role in gene regulation and apoptosis.Background & Unmet Need:The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and supp...
Published: 5/11/2010   |   Inventor(s): Michael Tainsky, Sylvia Dryden
Keywords(s): Compound, Protein
Category(s): Diagnostic, Antibodies, Life Science, Research tools
New Technology of Studying Protein Structure/Folding Functions in Living Mammalian Cells
This invention is a new protein transduction method for efficient delivery of exogenous proteins into mammalian cells. In contrast to known protein transduction methods, this new approach has the capability of targeting transduced proteins to different cellular compartments, as well as protecting the proteins from degradation by cellular proteases...
Published: 5/6/2010   |   Inventor(s): Qianqian Li, Jianjun Wang
Keywords(s): Protein
Category(s): Life Science, Reagents, Research tools