Search Results - compound

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SH80 Combinations

BackgroundSH35/SH80 evolved from an effort to improve upon the anti-tumor activity of XK469. XK469 is a compound, currently in Phase 1 clinical trials. The clinical trials include patients with bladder, breast, colorectal, esophageal, head and neck, kidney, liver, lung, mesothelioma, pancreas and sarcoma cancers. Moving a chlorine atom from one position...

Published: 3/2/2022 | Inventor(s): Lisa Polin

Keywords(s): Anti-cancer, Compound

Category(s): Life Science, Oncology, Therapeutics

Next Generation MRI Contrast Imaging Agent

WSU has developed a new class of contrast agents that are effective at ultra-high field strengths (>3 tesla) in magnetic resonance imaging (MRI) where current clinical agents severely decline in effectiveness. Our new agents are based on the metal Eu(II) which is novel compared to current agents that are based on Gd(III). The difference between the...

Published: 11/8/2021 | Inventor(s): Matthew Allen, Nipuni Gamage, Yujiang Mei, Joel Garcia, Jeremiah Moore

Keywords(s): Compound, Diagnostic, Imaging, MRI, Positive Imaging Agent

Category(s): Imaging, Chemicals, Life Science, MRI, Physical Sciences, Specialty compounds

SIRT2 Antibody

This technology is a novel rabbit antibody for SIRT2 ( Sirtuin 2) designed to follow human SIRT2 proteins in order to determine their role in gene regulation and apoptosis.Background & Unmet Need:The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress...

Published: 2/18/2022 | Inventor(s): Michael Tainsky, Sylvia Dryden

Keywords(s): Compound, Protein

Category(s): Diagnostic, Antibodies, Life Science, Research tools