Search Results - imaging




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Sentinel Cell
Sentry Cell (Macrophage Hazardous Material Detection) WSU Tech#: 10-991 Technology Summary: This technology is designed around an isolated cell system for the detection of an energetic material comprising of an isolated stationary macrophage cell isolated from a vestibular labyrinth of a Opsanus sp. This macrophage cell is plated in cultu...
Published: 5/19/2017   |   Inventor(s): Robert Silver
Keywords(s): Imaging, Process, Research Tool
Category(s): Process/Procedure, Biotechnology, Environment, Safety
Translation Regulated (TR)-Mediated Gene Expression: Novel Expression and Reporter Vectors
Background: Often referred to as the crucial "drug discovery tool", cell based technology is one of the most significant sectors of pharmaceutical research and development. Of particular importance has been the development of information-rich cellular assays that determine drug candidate efficacy and safety (target identification, valida...
Published: 8/14/2013   |   Inventor(s): Leon Carlock, Maria Cypher
Keywords(s): Animal Model, Anti-cancer, Cancer, Cancer risk, Cancer Therapies, Diagnostics, Imaging, Therapeutics
Category(s): Life Science, Diagnostics, Research tools, Assays, Cell lines
Laser Spray Ionization (LSI) Method for Mass Spectrometry Imaging
Technology Summary: Laser Spray Ionization (LSI) is a novel inlet ionization method for mass spectrometry invented at WSU which can be used to create predominately multiply charged ions from solid samples at atmospheric pressure. Unlike MALDI ionization methods which are typically limited to producing singly charged species for larger molecules, LS...
Published: 4/26/2013   |   Inventor(s): Sarah Trimpin, Thushani Nikeshala, Ellen Inutan, John Maarouf
Keywords(s): Biotechnology, Imaging
Category(s): Instrumentation, Imaging, Characterization, Other, Physical Sciences, Spectroscopy, Life Science, Research tools
Dual action nanocarrier combining CXCR4 antagonist and polyplex gene delivery for treatment of metastatic cancer and other diseases
Novel bio-reducible polymer compositions which combine the ability to act as a CXCR4 antagonist and simultaneously provide enhanced gene delivery through the formation of inert nanocarrier polyplexes have been developed. As would be expected for biodegradable polymers, the cytotoxicity of these nanocarrier compositions are very low with measured IC...
Published: 9/10/2012   |   Inventor(s): David Oupicky, Jing Li
Keywords(s): Cancer, Cancer Therapies, Compound, Drug Delivery, Drug Target, Formulation, Imaging, Nanomaterials, Pharmaceuticals, Therapeutics
Category(s): Drug Delivery, Gene Therapy, Therapeutics, Life Science, Oncology, Nano-based, Metabolic disorders, Biologicals
Next Generation MRI Contrast Imaging Agent
WSU has developed a new class of contrast agents that are effective at ultra-high field strengths (>3 tesla) in magnetic resonance imaging (MRI) where current clinical agents severely decline in effectiveness. Our new agents are based on the metal Eu(II) which is novel compared to current agents that are based on Gd(III). The difference between ...
Published: 8/2/2012   |   Inventor(s): Matthew Allen, Nipuni Gamage, Yujiang Mei, Joel Garcia, Jeremiah Moore
Keywords(s): Compound, Diagnostic, Imaging, MRI, Positive Imaging Agent
Category(s): Imaging, Chemicals, Life Science, MRI, Physical Sciences, Specialty compounds
Method For Treating and/or Imaging Breast Cancer Using Radioactive Iodine
This invention involves treating a breast cancer patient by the administration of a radioisotope of iodine in a dosage of between 5 and 50 milliCuries over the course of a day. The therapeutic composition is designed for mammary tissue uptake and includes an inorganic radioactive iodide salt (e.g., alkali metal, alkali earth or transition met...
Published: 5/18/2010   |   Inventor(s): James Rillema
Keywords(s): Anti-cancer, Breast Cancer, Cancer Therapies, Imaging, Therapeutics
Category(s): Therapeutics, Life Science, Oncology, Receptors/targets, Diagnostic, Imaging
Magnetic Resonance Force Microscopy for Molecular Imaging
This technology involves using refined Magnetic Resonance Force Microscopy (MRFM) to study biological systems such as isolated cells, sub-cellular organelles, and other sub-cellular structures or cellular receptors and proteins at resolutions ranging from 1 micron to 1 angstrom. MRFM has the potential to significantly impact biomedical research an...
Published: 5/13/2010   |   Inventor(s): Stanley Fricke, Gregory Moore
Keywords(s): Imaging
Category(s): Life Science, Research tools, Other