Search Results - biotechnology

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Generation of gp78 null mice WSU Tech#: 15-1291 Technology: Generation of the first preclinical experimental model system for gp78-/- C57BL/6 mice, which spontaneously develops age-related nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC), linking endoplasmic reticulum-associated degradation (ERAD) to hepatosteatosis, cirrhosis,...

Published: 11/22/2021 | Inventor(s): Avraham Raz, Andrei Golovko

Keywords(s):

Category(s): Animal models, Biology, Biomedical, Biotechnology, Drug Delivery, Drug Discovery, Drug Screening, Genomics/Genetics, Life Science, Oncology, Research tools

Sarcoidosis and TB Biomarkers

Sarcoidosis and TB Biomarkers WSU Tech#: 15-1276 Technology Summary: This technology includes a new method for generating phage libraries and clones that are useful in discovering biomarkers from human blood samples. The inventors looked at the change in immune cells versus that of the infected tissue (BAL and blood) used this to generate biomarkers...

Published: 3/2/2020 | Inventor(s): Lobelia Samavati, Harvinder Talwar, Felix Madrid, Rita Rosati, Jia Li

Keywords(s):

Category(s): Assays, Biotechnology, Diagnostic

GENERATION OF 5-FLUOROURACIL + OXALIPLATIN RESISTANT COLON CANCER CELLS: A TOOL TO STUDY CANCER RECURRENCE AND DRUG RESISTANCE

Generation of 5-Fluorouracil + Oxaliplatin Resistant Colon Cancer Cells WSU Tech#: 13-1154 Technology Summary: A significant obstacle for the successful management of patients with colorectal cancer (CRC) is intrinsic drug resistance or, in patients who respond to chemotherapy, acquired drug resistance. Drug resistance can occur through a variety...

Published: 11/19/2021 | Inventor(s): Adhip Majumdar, Yingjie Yu

Keywords(s):

Category(s): Biomedical, Biotechnology, Cell lines, Characterization, Drug Discovery, Oncology, Research tools

Long non-protein-coding RNA molecules as therapeutics for epilepsy.

Long Non-Coding RNA Molecules as Therapeutics for Epilepsy WSU Tech#: 12-1089 Technology Summary: Long Non-coding RNA (lncRNA) were first described in 2002 from mouse, making this a relatively new technology. lncRNA transcripts far exceed the number of protein coding mRNAs in the mammalian transcriptome, but in lower copy numbers. Inventors...

Published: 6/13/2025 | Inventor(s): Jeffrey Loeb, Leonard Lipovich

Keywords(s):

Category(s): Medical, Bioinformatics, Biomedical, Biotechnology, Diagnostic, Diagnostics, Drug Discovery, Pharmaceuticals, Therapeutics, Life Science

Sentinel Cell

Sentry Cell (Macrophage Hazardous Material Detection) WSU Tech#: 10-991 Technology Summary: This technology is designed around an isolated cell system for the detection of an energetic material comprising of an isolated stationary macrophage cell isolated from a vestibular labyrinth of a Opsanus sp. This macrophage cell is plated in...

Published: 1/9/2023 | Inventor(s): Robert Silver

Keywords(s): Imaging, Process, Research Tool

Category(s): Process/Procedure, Biotechnology, Environment, Safety