Search Results - animal+models




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Transgenic Mice Carrying Wild Type Human Her-2 Under the Whey Acidic Promoter
This technology is an animal model designed to help pharmaceutical and biotechnology industries develop Her-2 based vaccines or immunotherapeutic agents. Background & Unmet Need: Her-2 positive breast cancer is a breast cancer that is positive for a protein called human epidermal growth factor receptor 2 (Her-2). Presence of Her-2 promotes...
Published: 5/13/2025   |   Inventor(s): Wei-Zen Wei, Ye-Shih Ho, Marie Piechocki
Keywords(s): Animal Model, Breast Cancer, Research Tool
Category(s): Animal models, Life Science, Research tools
Generation of gp78 null mice
Generation of gp78 null mice WSU Tech#: 15-1291 Technology: Generation of the first preclinical experimental model system for gp78-/- C57BL/6 mice, which spontaneously develops age-related nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC), linking endoplasmic reticulum-associated degradation (ERAD) to hepatosteatosis, cirrhosis,...
Published: 11/22/2021   |   Inventor(s): Avraham Raz, Andrei Golovko
Keywords(s):  
Category(s): Animal models, Biology, Biomedical, Biotechnology, Drug Delivery, Drug Discovery, Drug Screening, Genomics/Genetics, Life Science, Oncology, Research tools