Search Results - animal model




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Translation Regulated (TR)-Mediated Gene Expression: Novel Expression and Reporter Vectors
Background: Often referred to as the crucial "drug discovery tool", cell based technology is one of the most significant sectors of pharmaceutical research and development. Of particular importance has been the development of information-rich cellular assays that determine drug candidate efficacy and safety (target identification, valida...
Published: 8/14/2013   |   Inventor(s): Leon Carlock, Maria Cypher
Keywords(s): Animal Model, Anti-cancer, Cancer, Cancer risk, Cancer Therapies, Diagnostics, Imaging, Therapeutics
Category(s): Life Science, Diagnostics, Research tools, Assays, Cell lines
Establishment of a Prostate Carcinoma Bone Tumor Model in Mice
This technology is a new tumorigenic cell line from the human prostate carcinoma cell line PC-3. These cell lines, known as PC-3/IF, when implanted in the femurs of nude mice, provide a xenograft tumor model of bone metastatic prostate carcinoma. The PC-3/IF cell lines are highly tumorigenic, with tumor cells replacing the marrow cells in the bon...
Published: 5/18/2010   |   Inventor(s): Gilda Hillman
Keywords(s): Animal Model, Prostate Cancer, Research Tool
Category(s): Animal models, Life Science, Research tools, Oncology, Diseases
Establishment of a Metastatic Prostate Carcinoma Tumor Model in Mice
This technology is a new tumorigenic cell line from the human prostate carcinoma cell line PC-3. These cell lines, known as PC-3/PI, are highly tumorigenic when implanted in the prostate of nude mice, providing a xenograft tumor model of prostate carcinoma. In this model, lymph node metastases form from the primary tumor, similar to what occurs i...
Published: 5/18/2010   |   Inventor(s): Gilda Hillman
Keywords(s): Animal Model, Cancer, Prostate Cancer, Research Tool
Category(s): Animal models, Life Science, Oncology, Research tools, Diseases
Establishment of a New Renal Cell Carcinoma Cell Line and a New Experimental Renal Tumor Model
This technology is a tumor cell line from a primary papillary renal cell carcinoma that, when implanted in the kidney of nude mice, provides a xenograft tumor model of human renal cell carcinoma. Background & Unmet Need: Renal cell carcinoma, which occurs in the parenchyma of the kidney, is the most common type of renal cancer, accounting for ...
Published: 5/18/2010   |   Inventor(s): Gilda Hillman
Keywords(s): Animal Model, Cancer, Research Tool
Category(s): Animal models, Life Science, Oncology, Research tools, Diseases