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A Gene Knockout Mouse Model to Study Lung
Disease
and a Lung Disease Drug Target
Our researchers have created a gene knockout mouse model that lacks the cytochrome c oxidase subunit IV-2 in order to study the gene’s effects on controlling asthma. Background & Unmeet Need: Asthma is an inflammatory
disease
of the airways that affects 155 million people of all ages worldwide. Cytochome c oxidase (CcO) is a multi-subunit...
Published: 12/17/2024
|
Inventor(s):
Maik Huettemann
,
Lawrence Grossman
,
David Bassett
Keywords(s):
Asthma
,
Disease
,
Drug Target
,
Gene
,
Knock-out
,
Lung
,
Mouse Model
Category(s):
Animal models
,
Biological materials
,
Life Science
,
Research tools
,
Protein/peptides
Antibacterial activity of natural compounds and their synthetic analogue: A potential new antibiotic with potent activity against multiple drug resistant bacterial pathogens
Our researchers have developed novel compounds that are potential new anti-infective therapeutics useful for treatment against the deadly bacteria MRSA (methicillin-resistant Staphylococcus aureus), VRE (vancomycin-resistant Enterococcus faecium), and several other well-known common infectious agents.Background & Unmet Need:Before antibiotics became...
Published: 8/9/2022
|
Inventor(s):
Hossein Salimnia
,
Fazlul Sarkar
,
Subhash Padhye
,
Bernhard Biersack
Keywords(s):
Analog or Analogue
,
Antibiotics
,
Anti-infective
,
Anti-microbial
,
Disease
Category(s):
Biologicals
,
Disease
s
,
Infectious
disease
,
Life Science
,
Therapeutics