Search Results - disease




2 Results Sort By:
A Gene Knockout Mouse Model to Study Lung Disease and a Lung Disease Drug Target
Our researchers have created a gene knockout mouse model that lacks the cytochrome c oxidase subunit IV-2 in order to study the gene’s effects on controlling asthma. Background & Unmeet Need: Asthma is an inflammatory disease of the airways that affects 155 million people of all ages worldwide. Cytochome c oxidase (CcO) is a multi-subunit...
Published: 12/17/2024   |   Inventor(s): Maik Huettemann, Lawrence Grossman, David Bassett
Keywords(s): Asthma, Disease, Drug Target, Gene, Knock-out, Lung, Mouse Model
Category(s): Animal models, Biological materials, Life Science, Research tools, Protein/peptides
Antibacterial activity of natural compounds and their synthetic analogue: A potential new antibiotic with potent activity against multiple drug resistant bacterial pathogens
Our researchers have developed novel compounds that are potential new anti-infective therapeutics useful for treatment against the deadly bacteria MRSA (methicillin-resistant Staphylococcus aureus), VRE (vancomycin-resistant Enterococcus faecium), and several other well-known common infectious agents.Background & Unmet Need:Before antibiotics became...
Published: 8/9/2022   |   Inventor(s): Hossein Salimnia, Fazlul Sarkar, Subhash Padhye, Bernhard Biersack
Keywords(s): Analog or Analogue, Antibiotics, Anti-infective, Anti-microbial, Disease
Category(s): Biologicals, Diseases, Infectious disease, Life Science, Therapeutics