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Search Results - drug+target
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A method to induce ferroptosis and to downregulate androgen receptor/androgen receptor splice variant in prostate cancer cells
Prostate cancer (PCa) effects approximately three million men in the United States every year. About 10-20% of the cases of prostate cancer are castrate-resistant prostate cancer (CRPC). This form of PCa is highly resistant to what Is known as androgen depletion therapy and is often fatal. All types of PCa are sensitive to androgen receptor signaling...
Published: 12/18/2024
|
Inventor(s):
Zhihui Qin
,
Liping Xu
Keywords(s):
Anti-cancer
,
Cancer
,
Cancer Therapies
,
Drug Delivery
,
Drug Target
,
Prostate Cancer
Category(s):
Medical
,
Diseases
,
Drug Discovery
,
Pharmaceuticals
,
Oncology
A Gene Knockout Mouse Model to Study Lung Disease and a Lung Disease
Drug Target
Our researchers have created a gene knockout mouse model that lacks the cytochrome c oxidase subunit IV-2 in order to study the gene’s effects on controlling asthma. Background & Unmeet Need: Asthma is an inflammatory disease of the airways that affects 155 million people of all ages worldwide. Cytochome c oxidase (CcO) is a multi-subunit...
Published: 12/17/2024
|
Inventor(s):
Maik Huettemann
,
Lawrence Grossman
,
David Bassett
Keywords(s):
Asthma
,
Disease
,
Drug Target
,
Gene
,
Knock-out
,
Lung
,
Mouse Model
Category(s):
Animal models
,
Biological materials
,
Life Science
,
Research tools
,
Protein/peptides