Search Results - avraham+raz

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Generation of gp78 null mice WSU Tech#: 15-1291 Technology: Generation of the first preclinical experimental model system for gp78-/- C57BL/6 mice, which spontaneously develops age-related nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC), linking endoplasmic reticulum-associated degradation (ERAD) to hepatosteatosis, cirrhosis,...

Published: 11/22/2021 | Inventor(s): Avraham Raz, Andrei Golovko

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Category(s): Animal models, Biology, Biomedical, Biotechnology, Drug Delivery, Drug Discovery, Drug Screening, Genomics/Genetics, Life Science, Oncology, Research tools

Level of Galectin-3 protein in human blood improves PSA test results

Level of Galectin-3 Protein in Human Blood Improves PSA Test Results WSU Tech#: 13-1133 Technology Summary: For determining prostate cancer aggressiveness, PSA alone is not reliable, as it gives a high number of false positive and false negative results. There are about 25,000 publications on other markers in addition to PSA and as of yet, none...

Published: 3/3/2020 | Inventor(s): Avraham Raz, Vitaly Balan, Elisabeth Heath, Lance Heilbrun

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Category(s): Medical, Biomedical, Diagnostics, Oncology

A Diagnostic Marker for Matrix Metalloprotease (MMP)-2 and -9 Activity in Cancer Tissue

This invention is a new and simple method for the identification of active versus latent matrix metalloprotease enzymes (MMPs) in tissue. Background & Unmet Need: MMPs are involved in tumor progression and therefore are targets for anti-cancer drug therapies. However, most drug therapies directed at inhibition of MMPs have failed because there...

Published: 11/22/2021 | Inventor(s): Avraham Raz, Rafael Fridman, Pratima Nangia-Makker

Keywords(s): Biomarker, Cancer, Diagnostics, Enzyme, Method

Category(s): Life Science, Oncology, Research tools, Antibodies, Therapeutics, Diseases