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Isoform-selective HDAC inhibitors
Selective C4-modified SAHA analogs inhibit HDAC6 and HDAC8 enzymes for targeted therapeutic applications.
Technology Summary
Histone deacetylase (HDAC) proteins are key players in cancer progression and have emerged recently as targets for anti-cancer drugs. WSU researchers have synthesized a variety of small molecule HDAC...
Published: 6/16/2026
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Inventor(s): Mary Pflum
Keywords(s):
Category(s): Technology Category > Biomedical, Technology Category > Chemical Processing/Synthesis, Technology Category > Characterization, Technology Category > Life Science, Technology Category > Oncology, Technology Category > Pharmaceuticals, Technology Category > Research tools, Technology Category > Small molecule
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Cell permeable ATP analogs
A novel ATP analog featuring a polyamine linker enables efficient kinase-catalyzed biotinylation within live cells by enhancing cell permeability.
Technology Summary
ATP (adenosine 5’-triphosphate) analogs such as ATP-biotin are widely used to monitor biochemical events in vitro. WSU researchers developed a specially...
Published: 6/16/2026
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Inventor(s): Mary Pflum
Keywords(s):
Category(s): Technology Category > Assays, Technology Category > Biology, Technology Category > Life Science, Technology Category > Research tools, Technology Category > Chemical Processing/Synthesis
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“Smart” Glucose-Responsive Insulin
Technology Summary
A "smart" or glucose-responsive insulin that can automatically respond to changes in a patient’s blood stream and help treat patients with type 1 diabetes. This technology comprises compositions that integrate a zwitterionic polymer, insulin moieties, saccharide moieties, and saccharide binding molecules to create...
Published: 1/9/2026
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Inventor(s): Zhiqiang Cao
Keywords(s):
Category(s): Technology Category > Biological materials, Technology Category > Chemical Processing/Synthesis, Technology Category > Drug Delivery, Technology Category > Process/Procedure, Technology Category > Small molecule, Technology Category > Therapeutics, Technology Category > Life Science
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Modified DGA-Associated Sorbent Media for Rare Earth Element Recovery
A novel hydrophobically modified diglycolamide (DGA) sorbent on organosilica enables selective, efficient, and sustainable recovery of rare earth elements (REEs) from low-grade and waste sources.
Technology Summary
This technology features a modified diglycolamide ligand, notably N,N,N,N-Tetraoctyl Diglycolamide (TODGA), functionalized with hydrophobic...
Published: 1/6/2026
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Inventor(s): Timothy Dittrich, Ahmed Sakr, Venkata Sai Praneeth Doranadula, Mohammed Dardona, Chandra Tummala
Keywords(s):
Category(s): Technology Category > Physical Sciences, Technology Category > Chemical Processing/Synthesis, Technology Category > Energy & Environment
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Thermal Atomic Layer Etching of Cobalt and Other Transition Metal Films
A novel stepwise chemical etching method for precise and controlled removal of metal surfaces using protic compounds.
Technology Summary
This technology introduces a method for etching metal or element surfaces by initially contacting the surface with a protic compound to create a modified layer, followed by exposure to a protic ligand-forming compound...
Published: 10/28/2025
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Inventor(s): Charles Winter
Keywords(s):
Category(s): Technology Category > Assays, Technology Category > Chemical Processing/Synthesis, Technology Category > Chemicals, Technology Category > Life Science, Technology Category > Materials, Technology Category > Physical Sciences, Technology Category > Physics, Technology Category > Process/Procedure, Technology Category > Small molecule, Technology Category > Specialty compounds, Technology Category > Thin films
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