Search Results - claudia turro




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Ruthenium-based caging of nitrile-containing enzyme inhibitors
Technology Summary: Novel synthesis methods for caging nitrile-containing bioactive molecules to a non-toxic ruthenium metal complex have been developed which enable light activated release of a cathespin K inhibitor. Numerous potent and selective cathepsin inhibitors are being developed as drug candidates. Cysteine cathepsins are involved in the pathophysiology...
Published: 4/29/2013   |   Inventor(s): Jeremy Kodanko, Claudia Turro
Keywords(s): Cancer, Pharmaceuticals
Category(s): Chemicals, Drug Delivery, Life Science, Physical Sciences, Other