Search Results - %22Life+Science%22+and+%22Infectious+Disease%22

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SALT-FORMULATED VALPROATE AS A TOPICAL ANTI-FUNGAL TREATMENT

In 2018, the global antifungal drugs market size was valued at USD 11.6 billion. Generally speaking, 54.3% of sales are prescription and 45.7% is over-the counter OTC/Alternative. It is anticipated that the OTC/Alternative portion of the global antifungal market will continue to grow. Science is indicating that both the number of systemic infections...

Published: 1/21/2022 | Inventor(s): Miriam Greenberg, Rania Deranieh

Keywords(s):

Category(s): Diseases, Infectious disease, Life Science, Small molecule, Pharmaceuticals

Activated T Cells and Activated T Cells Armed with BiSpecific Antibodies Directed at Cancer Antigens are Poor Responders to Alloantigens May Help Engraftment and Improve Anti-Tumor Effects

BackgroundThe treatment of hematologic malignancies with allogeneic stem cell transplant is limited by the numbers of allogeneic donors. Umbilical cord blood stem transplants have been an important alternative source of hematopoietic stem cells. However, failure or delayed engraftment remains the critical barrier to the success of the transplants....

Published: 3/2/2022 | Inventor(s): Lawrence Lum

Keywords(s): Anti-cancer

Category(s): Life Science, Therapeutics, Diseases, Infectious disease

Antibacterial activity of natural compounds and their synthetic analogue: A potential new antibiotic with potent activity against multiple drug resistant bacterial pathogens

Our researchers have developed novel compounds that are potential new anti-infective therapeutics useful for treatment against the deadly bacteria MRSA (methicillin-resistant Staphylococcus aureus), VRE (vancomycin-resistant Enterococcus faecium), and several other well-known common infectious agents.Background & Unmet Need:Before antibiotics became...

Published: 8/9/2022 | Inventor(s): Hossein Salimnia, Fazlul Sarkar, Subhash Padhye, Bernhard Biersack

Keywords(s): Analog or Analogue, Antibiotics, Anti-infective, Anti-microbial, Disease

Category(s): Biologicals, Diseases, Infectious disease, Life Science, Therapeutics

Using Flagellin to Prevent and to Treat Inflammation Associated Gram Negative Bacterial Infection

This technology provides a new method for treating inflammatory diseases by using a Gram negative bacterial component that results in increased tolerance and immunity. Background & Unmet Need: Despite advances of modern medicine, bacterial sepsis remains one of the major threats to human health worldwide. In the US alone, it affects approximately...

Published: 6/7/2022 | Inventor(s): Fu-Shin Yu, Ashok Kumar, Jing Zhang, Linda Hazlett

Keywords(s): Anti-microbial, Asthma

Category(s): Therapeutics, Diseases, Life Science, Infectious disease

Mannich Bases of Conjugated Styryl Ketones

Detailed Description Human infectious diseases caused by fungi have increased markedly during the past 10 years due mainly to advances in medical care that involve prolonged immune suppression increased use of cytotoxic drugs in cancer chemotherapy and the advent of AIDS. As a result organisms such as Candida albicans have become opportunistic...

Published: 2/27/2022 | Inventor(s): Jonathan Dimmock, Elias Manavathu

Keywords(s): Anti-infective, Therapeutics

Category(s): Therapeutics, Life Science, Infectious disease