Search Results - Biological materials




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Polyclonal and Monoclonal Antibodies to TPH1 and TPH2
This technology is a set of antibodies that is used with immunohistochemistry techniques to differentiate between tryptophan hydroxylase 1 and 2, enabling scientists to study how the two enzymes are differentially regulated. Background & Unmet Need: The tryptophan hydroxylase 1 and 2 (TPH1 and TPH2) genes encode enzymes in serotonin biosynthesis. ...
Published: 12/4/2019   |   Inventor(s): Donald Kuhn
Keywords(s): Antibody, Assay, Immunoassay
Category(s): Life Science, Research tools, Biological materials, Antibodies
EL4-E2 Cell Line
This technology is a targeted anti-HER2 cell line that can be used as a research tool to develop HER2‑based vaccines for the treatment of aggressive breast cancer. Background & Unmet Need: The human epidermal growth factor 2 (HER2) is overexpressed in approximately 20-30% of all breast cancers and is associated with more aggressive and proliferative...
Published: 9/17/2019   |   Inventor(s): Wei-Zen Wei
Keywords(s): Breast Cancer
Category(s): Cell lines, Life Science, Research tools, Biological materials
A Gene Knockout Mouse Model to Study Lung Disease and a Lung Disease Drug Target
Our researchers have created a gene knockout mouse model that lacks the cytochrome c oxidase subunit IV-2 in order to study the gene’s effects on controlling asthma. Background & Unmeet Need: Asthma is an inflammatory disease of the airways that affects 155 million people of all ages worldwide.  Cytochome c oxidase (CcO) is a multi-subunit enzyme located...
Published: 9/17/2019   |   Inventor(s): Maik Huttemann, Lawrence Grossman, David Bassett
Keywords(s): Asthma, Disease, Drug Target, Gene, Knock-out, Lung, Mouse Model
Category(s): Animal models, Biological materials, Life Science, Research tools, Protein/peptides
Lyophilized Ready to Use & Load PCR Master Mix
PCR and Enzyme Lyophilization and Stabilization Formulation  WSU Tech#: 13-1183Technology Summary: Wayne State University has discovered methods in which to formulate PCR related enzymes and reagents so they can be lyophilized.  This stabilizes the proteins, nucleotides and buffers so they can be shipped and stored at room temperature.  Our research...
Published: 5/19/2017   |   Inventor(s): Jian-Ping Jin
Keywords(s):  
Category(s): Biological materials, Research tools, Life Science
Peptide Antimicrobial
In vivo Display Technology for the Isolation of Antimicrobial Peptides Professor Philip R. Cunningham, Ph.D. Department of Biological Sciences @ Wayne State University Interest in peptides as antimicrobial agents has increased dramatically in recent years, driven primarily by the development of new technologies for producing, screening and analyzing...
Published: 5/3/2011   |   Inventor(s): Philip Cunningham, Wes Colangelo
Keywords(s):  
Category(s): Pharmaceuticals, Life Science, Research tools, Assays, Biological materials, Protein/peptides