Search Results - libo wu




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Co-polymer Stabilizers for Pressured Metered Dose Inhalers (pMDIs)
A series of novel co polymer surfactants with the general structure LAmEOnLAm were developed along with a Colloidal Probe Microscopy (CPM) method to optimize the surfactant composition using adhesion forces to improve stabilization of drug dispersions. This expands the range of biomolecules and micronized drug particles that can be formulated with pMDIs....
Published: 8/14/2013   |   Inventor(s): Sandro Da Rocha, Libo Wu
Keywords(s): Assay, Asthma, Compound, Device, Drug Delivery, Formulation, Instrumentation, Method, Pharmaceuticals, Process, Therapeutics
Category(s): Chemicals, Drug Delivery, Pharmaceuticals, Instrumentation, Materials
Nanoparticle Method to Stabilize Suspension-Based pMDI HFA Formulations
Novel nanoparticle-based drug compositions and methods that improve and expand therapeutic drug delivery to the lungs through pressurized meter-dose inhalers (pMDIs). A large variety of approaches have been developed at WSU aimed at improving the aerosol characteristics and expanding the range of target species deliverable. These improved formulations...
Published: 4/23/2013   |   Inventor(s): Sandro Da Rocha, Libo Wu
Keywords(s): Asthma, Drug Delivery, Formulation, Nanomaterials, Pharmaceuticals
Category(s): Drug Delivery, Life Science, Nano-based, Therapeutics
Improved pDMI Inhaler Formulations
Novel biodegradable, non-toxic nanoparticles that act as stabilizing excipients with a wide variety of suspension drug candidates including polar & non-polar drug particles, bio-macromolecules (proteins/peptides), gene therapies (DNA/siRNA) as well as amorphous and crystalline therapeutics have been developed which provide a platform for improving...
Published: 5/6/2010   |   Inventor(s): Sandro Da Rocha, Libo Wu
Keywords(s): Asthma, Drug Delivery, Formulation, Nanomaterials, Pharmaceuticals, Therapeutics
Category(s): Drug Delivery, Life Science, Therapeutics, Nano-based