Search Results - Physical+Sciences

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Low-Power, Multi-Phase, CMOS-based Ring Oscillator Circuit Background: CMOS technology is used for constructing integrated circuit (IC) chips, including microprocessors, microcontrollers, memory chips (including CMOS BIOS), and other analog and digital logic circuits. A CMOS ring oscillator circuit is an odd number (N) of inverting stages connected...

Published: 12/6/2022 | Inventor(s): Melvin Edwards II, Mohammad Alhawari

Keywords(s): IoT

Category(s): Communications, Physical Sciences, Electronics, Electrical

Novel Microsensor Design to Improve Data Collection From Hard-To-Monitor Environments

Wireless microsensors have enabled new ways to monitor our environment by allowing users to measure spaces previously off limits to research, such as toxic areas, vehicle components, or remote areas in the human body. Researchers, however, have been stymied by limited improvements in the quality of data and sensitivity of these devices stemming from...

Published: 4/20/2023 | Inventor(s): Pai-Yen Chen, Maryam Sakhdari, Mehdi Hajizadegan, Mark Ming-Cheng Cheng

Keywords(s): Device, Sensors

Category(s): MEMS, Physical Sciences, Sensors

Porous Biodegradable Polymers for Bone Grafts

Technology Summary: A novel polymer nanocomposites has been developed as a potential alternative to autografts and allografts in orthopedic procedures requiring bone grafting. Supercritical CO2 processing of resorbable polymer/nano-clay mixtures results in the formation of porous nanocomposite constructs which exhibit biocompatibility and significant...

Published: 11/11/2021 | Inventor(s): Rangaramanujam Kannan, Kevin Baker, Robert Bellair, Mihai Manitiu, Harry Herkowitz

Keywords(s):

Category(s): Materials, Life Science, Medical Devices, Biomaterials, Nanomaterials, Physical Sciences, Polymer

Ruthenium-based caging of nitrile-containing enzyme inhibitors

Technology Summary: Novel synthesis methods for caging nitrile-containing bioactive molecules to a non-toxic ruthenium metal complex have been developed which enable light activated release of a cathespin K inhibitor. Numerous potent and selective cathepsin inhibitors are being developed as drug candidates. Cysteine cathepsins are involved in the pathophysiology...

Published: 10/27/2023 | Inventor(s): Jeremy Kodanko, Claudia Turro

Keywords(s): Cancer, Pharmaceuticals

Category(s): Chemicals, Drug Delivery, Life Science, Physical Sciences, Other

Laser Spray Ionization (LSI) Method for Mass Spectrometry Imaging

Technology Summary: Laser Spray Ionization (LSI) is a novel inlet ionization method for mass spectrometry invented at WSU which can be used to create predominately multiply charged ions from solid samples at atmospheric pressure. Unlike MALDI ionization methods which are typically limited to producing singly charged species for larger molecules, LSI...

Published: 5/1/2018 | Inventor(s): Sarah Trimpin, Thushani Nikeshala, Ellen Inutan, John Maarouf

Keywords(s): Biotechnology, Imaging

Category(s): Instrumentation, Imaging, Characterization, Other, Physical Sciences, Spectroscopy, Life Science, Research tools

Next Generation MRI Contrast Imaging Agent

WSU has developed a new class of contrast agents that are effective at ultra-high field strengths (>3 tesla) in magnetic resonance imaging (MRI) where current clinical agents severely decline in effectiveness. Our new agents are based on the metal Eu(II) which is novel compared to current agents that are based on Gd(III). The difference between the...

Published: 11/8/2021 | Inventor(s): Matthew Allen, Nipuni Gamage, Yujiang Mei, Joel Garcia, Jeremiah Moore

Keywords(s): Compound, Diagnostic, Imaging, MRI, Positive Imaging Agent

Category(s): Imaging, Chemicals, Life Science, MRI, Physical Sciences, Specialty compounds

Intelligent Autonomous Camera Control for Robotics with Medical, Military, & Space Applications

Currently, during robotic surgery the surgeon must interrupt the operation and shift controls to move the camera arm of the robot, causing a distraction for the surgeon. Researchers from Wayne State University’s Electrical and Computer Engineering Department and the School of Medicine have jointly developed a new method for camera movement based on...

Published: 9/10/2021 | Inventor(s): Abhilash Pandya, Michael Klein, Ajay Mudunuri, Alex Cao, Luke Reisner, Brady King, Syed Ali

Keywords(s):

Category(s): Devices, Medical Devices, Life Science, Physical Sciences, Electronics, Robotics

Integration of 1-D MnO2 Nanowire and 2-D Graphene to 3-D Composites and their Applications in High-Energy, High-Power and Low-Cost Aqueous Supercapacitors

Wayne State University researchers have developed a novel method for the preparation of unique 3-D composites of conductive graphene and high capacitance MnO2 as electrode materials, to fabricate asymmetric aqueous supercapacitors for energy-storage applications. Currently MnO2 is commonly coated onto current collectors to form very thin films...

Published: 4/16/2021 | Inventor(s): Lixin Wang, Da Deng, Ka Yuen Simon Ng

Keywords(s):

Category(s): Materials, Nanomaterials, Physical Sciences, Energy & Environment, Energy Storage/Battery

Enhanced Peripheral Detection Test-I (EPDT-I) Enhanced Peripheral Detection Test-II (EPDT-II)

Wayne State University researchers have teamed up with the Toyota Technical Center, a division of Toyota Motor Engineering & Manufacturing North America, Inc. (TEMA), to work on projects for TEMA's safety research center -- the Collaborative Safety Research Center (CSRC). One technology under development is a software program related to driver distraction: •Method...

Published: 11/11/2021 | Inventor(s): Li Hsieh, Richard Young, Sean Seaman

Keywords(s):

Category(s): Software, Automotive & Transportation, Physical Sciences, Safety

Atomic Layer Deposition of Transition Metal Thin Films

Wayne State University researchers have circumvented precursor reactivity problems by developing a three-step deposition scheme that entails a transition metal precursor, an organic acid, and a reducing agent. This novel process can produce high purity, low resistivity copper films at 100 °C, which is a significant breakthrough in transition metal ALD...

Published: 12/2/2021 | Inventor(s): Charles Winter, Thomas Knisley, Thiloka Ariyasena

Keywords(s):

Category(s): Materials, Nanomaterials, Physical Sciences, Thin films, Chemical Processing/Synthesis, Industrial & Manufacturing

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