Search Results - Physical+Sciences

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Low-Power, Multi-Phase, CMOS-based Ring Oscillator Circuit Background: CMOS technology is used for constructing integrated circuit (IC) chips, including microprocessors, microcontrollers, memory chips (including CMOS BIOS), and other analog and digital logic circuits. A CMOS ring oscillator circuit is an odd number (N) of inverting stages connected...

Published: 12/6/2022 | Inventor(s): Melvin Edwards II, Mohammad Alhawari

Keywords(s): IoT

Category(s): Communications, Physical Sciences, Electronics, Electrical

Ruthenium-based caging of nitrile-containing enzyme inhibitors

Technology Summary: Novel synthesis methods for caging nitrile-containing bioactive molecules to a non-toxic ruthenium metal complex have been developed which enable light activated release of a cathespin K inhibitor. Numerous potent and selective cathepsin inhibitors are being developed as drug candidates. Cysteine cathepsins are involved in the pathophysiology...

Published: 10/27/2023 | Inventor(s): Jeremy Kodanko, Claudia Turro

Keywords(s): Cancer, Pharmaceuticals

Category(s): Chemicals, Drug Delivery, Life Science, Physical Sciences, Other

Laser Spray Ionization (LSI) Method for Mass Spectrometry Imaging

Technology Summary: Laser Spray Ionization (LSI) is a novel inlet ionization method for mass spectrometry invented at WSU which can be used to create predominately multiply charged ions from solid samples at atmospheric pressure. Unlike MALDI ionization methods which are typically limited to producing singly charged species for larger molecules, LSI...

Published: 5/1/2018 | Inventor(s): Sarah Trimpin, Thushani Nikeshala, Ellen Inutan, John Maarouf

Keywords(s): Biotechnology, Imaging

Category(s): Instrumentation, Imaging, Characterization, Other, Physical Sciences, Spectroscopy, Life Science, Research tools

Next Generation MRI Contrast Imaging Agent

WSU has developed a new class of contrast agents that are effective at ultra-high field strengths (>3 tesla) in magnetic resonance imaging (MRI) where current clinical agents severely decline in effectiveness. Our new agents are based on the metal Eu(II) which is novel compared to current agents that are based on Gd(III). The difference between the...

Published: 11/8/2021 | Inventor(s): Matthew Allen, Nipuni Gamage, Yujiang Mei, Joel Garcia, Jeremiah Moore

Keywords(s): Compound, Diagnostic, Imaging, MRI, Positive Imaging Agent

Category(s): Imaging, Chemicals, Life Science, MRI, Physical Sciences, Specialty compounds

Intelligent Autonomous Camera Control for Robotics with Medical, Military, & Space Applications

Currently, during robotic surgery the surgeon must interrupt the operation and shift controls to move the camera arm of the robot, causing a distraction for the surgeon. Researchers from Wayne State University’s Electrical and Computer Engineering Department and the School of Medicine have jointly developed a new method for camera movement based on...

Published: 9/10/2021 | Inventor(s): Abhilash Pandya, Michael Klein, Ajay Mudunuri, Alex Cao, Luke Reisner, Brady King, Syed Ali

Keywords(s):

Category(s): Devices, Medical Devices, Life Science, Physical Sciences, Electronics, Robotics

Marangoni Optofluidic Tweezers (MOT)

There is currently a great deal of interest in using small droplets as containers for chemical reactions. Optical methods for droplet manipulation are attractive because they offer control without an on chip structure; however forces from optical tweezers tend to be in the pN range. Wayne State University researchers have developed a new method...

Published: 5/19/2017 | Inventor(s): Amar Basu, Gopakumar Kamalakshakurup

Keywords(s):

Category(s): MEMS, Microfluidics, Physical Sciences, Instrumentation, Optics & Photonics

Dispersion-optimized Silicon nanoparticle (SiNP)/Graphene composite anode for high performance Lithium ion battery (LIB)

WSU researchers have invented a novel method to produce dispersion-optimized SiNP within a conducting Graphene matrix forming a standalone composite anode material. The method creates small clusters to lone particle distributions maximizing the nanomaterial properties of SiNP yielding anodes with improved capacity retention and rate performance. It...

Published: 8/26/2021 | Inventor(s): Rhet C De Guzman, Ka Yuen Simon Ng, Steven Salley

Keywords(s):

Category(s): Chemicals, Materials, Energy & Environment, Energy Storage/Battery, Nanomaterials, Physical Sciences

First Row Transition Metal Diazadiene Film Growth Precursors

Technology Overview Wayne State University researchers have developed a new class of thermally stable, volatile transition chemical compounds that have desirable properties for the growth of thin films of transition metal-containing materials. These novel film precursors have high potential for use in the growth of thin films by chemical vapor...

Published: 3/12/2018 | Inventor(s): Charles Winter, Thomas Knisley

Keywords(s):

Category(s): Chemicals, Materials, Other, Physical Sciences, Thin films

Vibro-acoustic metamaterial with mass and flexible stem array

WSU researchers have developed a novel device combining the effects of negative effective elastic modulus and negative effective mass, acting as local resonators that can damp out vibrations and sound at multiple frequencies. This class of metamaterials has the superior ability to attenuate sound and have a much greater ability to block dynamic disturbances....

Published: 9/10/2021 | Inventor(s): Md Tofiqul Islam, Golam Newaz, Mohammad Hailat

Keywords(s):

Category(s): Materials, Industrial & Manufacturing, Other, Physical Sciences, Building & Construction

Concussion Reduction Helmet

Wayne State University Researchers have designed a football helmet to reduce the likelihood of a cerebral concussion to the wearer during blunt impact with another player or the ground. The helmet shell and interior padding are tuned using a computer model of the head and helmet to reduce the strain experienced by the brain during impact. Commercial...

Published: 11/30/2023 | Inventor(s): Albert King, King-Hay Yang, Liying Zhang

Keywords(s):

Category(s): Physical Sciences, Automotive & Transportation, Life Science, Medical Devices, Safety, Simulation & Modeling

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